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Anti-GPNMB Monoclonal Antibody (3X881)
(Synonyms: NMB, HGFIN) Copy Product Info
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Synonyms: NMB, HGFIN
Catalog No. TMAC-01701 Copy Product Info
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Anti-GPNMB Monoclonal Antibody (3X881) is a Mouse antibody targeting GPNMB. Anti-GPNMB Monoclonal Antibody (3X881) can be used in WB,IHC.
Anti-GPNMB Monoclonal Antibody
(3X881)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 µL | $296 | 7-10 days | 7-10 days | |
| 100 µL | $427 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-GPNMB Monoclonal Antibody (3X881) is a Mouse antibody targeting GPNMB. Anti-GPNMB Monoclonal Antibody (3X881) can be used in WB,IHC. |
| Synonyms | NMB, HGFIN |
| Ig Type | IgG1 |
| Clone | 3X881 |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of GPNMB on human GPNMB recombinant protein using anti-GPNMB antibody at 1/1,000 dilution. 2. Western blot analysis of GPNMB on HEK293 (1) and GPNMB-hIgGFc transfected HEK293 (2) cell lysate using anti-GPNMB antibody at 1/1,000 dilution. 3. Western blot analysis of GPNMB on PANC-1 and PC-3 cell lysate using anti-GPNMB antibody at 1/1,000 dilution. 4. Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using anti-GPNMB antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded human esophagus cancer tissue using anti-GPNMB antibody. Counter stained with hematoxylin.  , , , , |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human GPNMB (AA: 31-260) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | GPNMB |
| Gene ID | |
| Protein Name | Transmembrane glycoprotein NMB |
| Uniprot ID |
| Molecular Weight | Theoretical: 64 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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