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Anti-Osteoactivin/GPNMB Antibody (4G206)

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Catalog No. TMAC-01701
Alias Osteoactivin, NMB, HGFIN, glycoprotein (transmembrane) nmb

Anti-Osteoactivin/GPNMB Antibody (4G206) is a Mouse antibody targeting Osteoactivin/GPNMB. Anti-Osteoactivin/GPNMB Antibody (4G206) can be used in WB,IHC.

Anti-Osteoactivin/GPNMB Antibody (4G206)

Anti-Osteoactivin/GPNMB Antibody (4G206)

😃Good
Catalog No. TMAC-01701Alias Osteoactivin, NMB, HGFIN, glycoprotein (transmembrane) nmb
Anti-Osteoactivin/GPNMB Antibody (4G206) is a Mouse antibody targeting Osteoactivin/GPNMB. Anti-Osteoactivin/GPNMB Antibody (4G206) can be used in WB,IHC.
Pack SizePriceAvailabilityQuantity
50 μL$2967-10 days
100 μL$4277-10 days
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Product Introduction

Bioactivity
Description
Anti-Osteoactivin/GPNMB Antibody (4G206) is a Mouse antibody targeting Osteoactivin/GPNMB. Anti-Osteoactivin/GPNMB Antibody (4G206) can be used in WB,IHC.
SynonymsOsteoactivin, NMB, HGFIN, glycoprotein (transmembrane) nmb
Clone
4G206
Reactivity
Human
Verified Activity
1. Western blot analysis of GPNMB on human GPNMB recombinant protein using anti-GPNMB antibody at 1/1,000 dilution.
2. Western blot analysis of GPNMB on HEK293 (1) and GPNMB-hIgGFc transfected HEK293 (2) cell lysate using anti-GPNMB antibody at 1/1,000 dilution.
3. Western blot analysis of GPNMB on PANC-1 and PC-3 cell lysate using anti-GPNMB antibody at 1/1,000 dilution.
4. Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using anti-GPNMB antibody. Counter stained with hematoxylin.
5. Immunohistochemical analysis of paraffin-embedded human esophagus cancer tissue using anti-GPNMB antibody. Counter stained with hematoxylin.
Application
Recommended Dose
WB: 1:500; IHC: 1:100-200
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundTransmembrane glycoprotein NMB (GPNMB), also designated hematopoietic growth factor inducible neurokinin-1 (HGFIN), is a single-pass type I membrane protein. Belonging to the Pmel-17/NMB family of proteins, GPNMB acts as a melanogenic enzyme. GPNMB expression is not restricted to cells of melanocytic lineage and is highest in poorly metastatic melanoma cell lines. There is no expression of GPNMB in highly metastatic melanoma cell lines. GPNMB may play a important role in lymphohematopoietic stem cell maturation.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 64 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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