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Anti-Meprin alpha/MEP1A Antibody (2Q198)
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Catalog No. TMAY-03064
Alias PPHA, Meprin α/MEP1A, meprin A, α (PABA peptide hydrolase), meprin A, alpha (PABA peptide hydrolase)
Anti-Meprin alpha/MEP1A Antibody (2Q198) is a Rabbit antibody targeting Meprin alpha/MEP1A. Anti-Meprin alpha/MEP1A Antibody (2Q198) can be used in ELISA,IHC-P.
Anti-Meprin alpha/MEP1A Antibody (2Q198)
Anti-Meprin alpha/MEP1A Antibody (2Q198)
😃Good
Catalog No. TMAY-03064Alias PPHA, Meprin α/MEP1A, meprin A, α (PABA peptide hydrolase), meprin A, alpha (PABA peptide hydrolase)
Anti-Meprin alpha/MEP1A Antibody (2Q198) is a Rabbit antibody targeting Meprin alpha/MEP1A. Anti-Meprin alpha/MEP1A Antibody (2Q198) can be used in ELISA,IHC-P.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: ELISA, IHC-P Reactivity: Mouse |
| Alias | PPHA, Meprin α/MEP1A, meprin A, α (PABA peptide hydrolase), meprin A, alpha (PABA peptide hydrolase) |
| Ig Type | Rabbit IgG |
| Clone | 2Q198 |
| Reactivity | Mouse |
| Verified Activity | 1. Immunochemical staining of mouse MEP1A in mouse kidney with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of mouse MEP1A in mouse intestine with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). The left panel: tissue incubated with primary antibody; The right panel: tissue incubated with the mixture of primary antibody and antigen (recombinant protein). |
| Application | ELISA,IHC-P |
| Recommended Dose | ELISA: 1:5000-1:10000; IHC-P: 1:100-1:500 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse MEP1A (rM MEP1A; TMPY-01318; NP_032611.2; Met 1-Arg 615). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Meprin A subunit alpha, also known as MEP1A, and Endopeptidase-2, is a single-pass type I membrane protein that belongs to the peptidase M12A family. MEP1A contains one EGF-like domain, one MAM domain, and one MATH domain. Meprins are unique plasma membrane and secreted metalloproteinases that are highly regulated at the transcriptional and post-translational levels. Meprin alpha and beta subunits are abundantly expressed in kidney and intestinal epithelial cells, are secreted into the urinary tract and intestinal lumen and are found in leukocytes and cancer cells under certain conditions. Meprins are capable of proteolytically degrading extracellular matrix proteins, processing bioactive proteins, and play a role in inflammatory processes. Meprin A and B are highly regulated, secreted and cell-surface homo- and hetero-oligomeric enzymes. Meprins are abundantly expressed in the kidney and intestine. The multidomain alpha and beta subunits have high sequence identity. They have very different substrate specificities, oligomerization potentials, and are differentially regulated. Meprin A appears to be an important therapeutic target and urinary excretion appears to be a potential biomarker of acute kidney injury ( AKI ). |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Mouse MEP1A Protein (TMPY-01318) |
| Antigen Species | Mouse |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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