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Anti-PMVK Antibody (2Z739) is a Rabbit antibody targeting PMVK. Anti-PMVK Antibody (2Z739) can be used in ELISA,IHC-P.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $270 | 7-10 days |
Description | Anti-PMVK Antibody (2Z739) is a Rabbit antibody targeting PMVK. Anti-PMVK Antibody (2Z739) can be used in ELISA,IHC-P. |
Alias | PMKASE, PMKA, PMK, phosphomevalonate kinase, HUMPMKI |
Ig Type | Monoclonal Rabbit IgG |
Clone | 2Z739 |
Reactivity | Human |
Verified Activity | 1. Immunochemical staining of human PMVK in human skeletal muscle with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human PMVK in human pancreas with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 3. Immunochemical staining of human PMVK in human liver with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). |
Application | ELISA,IHC-P |
Recommended Dose | ELISA: 1:5000-1:10000; IHC-P: 1:100-1:500 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human PMVK / phosphomevalonate kinase (rh PMVK / phosphomevalonate kinase; TMPY-04767; Q15126; Met1-Leu192). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | PMVK is a peroxisomal enzyme that catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate, the fifth reaction of the cholesterol biosynthetic pathway. Studies in rat show that the message level and the enzyme activity of PMVK is regulated by sterol, and that this regulation is coordinated with 3-hydroxy-3-methylglutaryl coenzyme A reductase, the rate-limiting enzyme of cholesterol biosynthesis. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human PMVK / phosphomevalonate kinase Protein (TMPY-04767) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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