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Anti-PMVK Antibody (2Z739)

😃Good
Catalog No. TMAY-02761
Alias PMKASE, PMKA, PMK, phosphomevalonate kinase, HUMPMKI

Anti-PMVK Antibody (2Z739) is a Rabbit antibody targeting PMVK. Anti-PMVK Antibody (2Z739) can be used in ELISA,IHC-P.

Anti-PMVK Antibody (2Z739)

Anti-PMVK Antibody (2Z739)

😃Good
Catalog No. TMAY-02761Alias PMKASE, PMKA, PMK, phosphomevalonate kinase, HUMPMKI
Anti-PMVK Antibody (2Z739) is a Rabbit antibody targeting PMVK. Anti-PMVK Antibody (2Z739) can be used in ELISA,IHC-P.
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100 μL$270 7-10 days
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Product Introduction

Bioactivity
Description
Anti-PMVK Antibody (2Z739) is a Rabbit antibody targeting PMVK. Anti-PMVK Antibody (2Z739) can be used in ELISA,IHC-P.
AliasPMKASE, PMKA, PMK, phosphomevalonate kinase, HUMPMKI
Ig Type
Monoclonal Rabbit IgG
Clone
2Z739
Reactivity
Human
Verified Activity
1. Immunochemical staining of human PMVK in human skeletal muscle with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).

2. Immunochemical staining of human PMVK in human pancreas with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).

3. Immunochemical staining of human PMVK in human liver with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).
Application
ELISA,IHC-P
Recommended Dose
ELISA: 1:5000-1:10000; IHC-P: 1:100-1:500
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human PMVK / phosphomevalonate kinase (rh PMVK / phosphomevalonate kinase; TMPY-04767; Q15126; Met1-Leu192).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundPMVK is a peroxisomal enzyme that catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate, the fifth reaction of the cholesterol biosynthetic pathway. Studies in rat show that the message level and the enzyme activity of PMVK is regulated by sterol, and that this regulation is coordinated with 3-hydroxy-3-methylglutaryl coenzyme A reductase, the rate-limiting enzyme of cholesterol biosynthesis.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human PMVK / phosphomevalonate kinase Protein (TMPY-04767)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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