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TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc)
(Synonyms: TβR-II, Transforming growth factor-β receptor type II, Transforming growth factor-beta receptor type II, TGF-β type II receptor, TGF-β receptor type-2, TGF-β receptor type II, TGFR-2, Tgfbr2, TGF-beta type II receptor, TGF-beta receptor type-2, TGF-beta receptor type II, TbetaR-II) Copy Product InfoSynonyms: TβR-II, Transforming growth factor-β receptor type II, Transforming growth factor-beta receptor type II, TGF-β type II receptor, TGF-β receptor type-2, TGF-β receptor type II, TGFR-2, Tgfbr2, TGF-beta type II receptor, TGF-beta receptor type-2, TGF-beta receptor type II, TbetaR-II
Catalog No. TMPJ-00334 Copy Product Info
TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 55-65 KDa and the accession number is Q62312-2.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $58 | 7-10 days | 7-10 days | |
| 10 µg | $91 | 7-10 days | 7-10 days | |
| 20 µg | $133 | 7-10 days | 7-10 days | |
| 50 µg | $222 | 7-10 days | 7-10 days | |
| 100 µg | $397 | 7-10 days | 7-10 days | |
| 200 µg | $715 | 7-10 days | 7-10 days | |
| 500 µg | $1,570 | 7-10 days | 7-10 days | |
| 1 mg | $2,230 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Measured by its ability to inhibit TGF-beta 1 activity on TF‑1 human erythroleukemic cells. The ED50 for this effect is 69.07 ng/ml in the presence of 1ng/ml of recombinant human TGF-beta 1. (Regularly tested) |
| Description | TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 55-65 KDa and the accession number is Q62312-2. |
| Species | Mouse |
| Expression System | HEK293 Cells |
| Tag | C-hFc |
| Accession Number | Q62312-2 |
| Amino Acid | Ile24-Asp159 |
| Construction | Ile24-Asp159 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | TβR-II, Transforming growth factor-β receptor type II, Transforming growth factor-beta receptor type II, TGF-β type II receptor, TGF-β receptor type-2, TGF-β receptor type II, TGFR-2, Tgfbr2, TGF-beta type II receptor, TGF-beta receptor type-2, TGF-beta receptor type II, TbetaR-II |
| Research Background | Transforming growth factor-β (TGF-β) is an essential regulator in the processes of development, cell proliferation, and extracellular matrix deposition. TGF-β regulates cellular processes by binding to three high-affinity cell surface receptors: TGF-β receptor type I (TGF-β-RI), TGF-β receptor type II (TGF-β-RII), and TGF-ββ receptor type III (TGF-β-RIII). TGF-β RII is consists of a C-terminal protein kinase domain and an N-terminal ectodomain and belongs to transforming growth factor-beta (TGF-β) receptor subfamily. TGF-β RII has a protein kinase domain which can form a heterodimeric complex with another receptor protein and bind TGF-beta. This receptor/ligand complex phosphorylates protein will enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. |
| Molecular Weight | 55-65 KDa (reducing condition) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc) chemical structure | TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc) molecular weight
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