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Anti-Cyclophilin B Antibody (1B168) (Synonyms: SCYLP, peptidylprolyl isomerase B (cyclophilin B), OI9, HEL-S-...)

Catalog No. TMAC-01055 Copy Product Info
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Anti-Cyclophilin B Antibody (1B168) is a Rabbit antibody targeting Cyclophilin B. Anti-Cyclophilin B Antibody (1B168) can be used in WB.

Anti-Cyclophilin B Antibody (1B168)

Copy Product Info
🥰Excellent
Catalog No. TMAC-01055
Synonyms SCYLP, peptidylprolyl isomerase B (cyclophilin B), OI9, HEL-S-39, CYP-S1, CYPB

Anti-Cyclophilin B Antibody (1B168) is a Rabbit antibody targeting Cyclophilin B. Anti-Cyclophilin B Antibody (1B168) can be used in WB.

Anti-Cyclophilin B Antibody
(1B168)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2987-10 days7-10 days
100 μL$4987-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Cyclophilin B Antibody (1B168) is a Rabbit antibody targeting Cyclophilin B. Anti-Cyclophilin B Antibody (1B168) can be used in WB.
SynonymsSCYLP, peptidylprolyl isomerase B (cyclophilin B), OI9, HEL-S-39, CYP-S1, CYPB
Ig Type
IgG
Clone
1B168
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of Cyclophilin B on different lysates using anti-Cyclophilin B antibody at 1/1,000 dilution. Positive control: Lane 1: Hela, Lane 2: HepG2, Lane 3: NIH/3T3.
verifiedActivity
Application
Recommended Dose
WB: 1:1000-5000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundThe immunosuppressant cyclosporin A (CsA) forms a trimolecular complex with cyclophilin and calcineurins to inhibit calcineurin phosphatase activity. Cyclophilins are conserved, ubiquitous and abundant cytosolic peptidyl-prolyl cis-trans isomerases that accelerate the isomerization of XaaPro peptide bonds and the refolding of proteins. Human cyclophilin A (CyPA), an intracellular protein of 165 amino acids, is the target of the Cyclosporin A and is encoded by a single unique gene conserved from yeast to humans. CyPA is known for its involvement in T cell differentiation and proliferation and is highly expressed in brain. CyPA is incorporated into the virion of the type 1 human immunodeficiency virus (HIV-1) via a direct interaction with the capsid domain of the viral Gag polyprotein and is crucial for efficient viral replication. Cyclophilin B (CyPB) is a member of the cyclophilin family with specific N- and C-terminal extensions. Unlike CyPA, CyPB has a signal sequence leading to its translocation in the endoplasmic reticulum. CyPB is secreted in biological fluids such as blood or milk and binds to a specific receptor present on the human lymphoblastic cell line Jurkat and on human peripheral blood lymphocytes.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 18 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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