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Anti-CEACAM6 Antibody-APC (1L889)
🥰Excellent
Catalog No. TMAY-01222A
Anti-CEACAM6 Antibody-APC (1L889) is a APC-conjugated Rabbit antibody targeting CEACAM6. Anti-CEACAM6 Antibody-APC (1L889) can be used in FCM.
Anti-CEACAM6 Antibody-APC (1L889)
Anti-CEACAM6 Antibody-APC (1L889)
🥰Excellent
Catalog No. TMAY-01222A
Anti-CEACAM6 Antibody-APC (1L889) is a APC-conjugated Rabbit antibody targeting CEACAM6. Anti-CEACAM6 Antibody-APC (1L889) can be used in FCM.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CEACAM6 Antibody-APC (1L889) is a APC-conjugated Rabbit antibody targeting CEACAM6. Anti-CEACAM6 Antibody-APC (1L889) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 1L889 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of human CEACAM6 expression on human whole blood granulocytes. Human whole blood granulocytes were stained with APC-conjugated anti-Human CEACAM6. The histogram were derived from gated events with the forward and side light-scatter characteristics of viable granulocytes. |
| Application | FCM |
| Recommended Dose | 10 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human CEACAM6 / CD66c (rh CEACAM6 / CD66c; 10823-H08H; Met 1-Gly 320; NP_002474.4) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Research Background | Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6), also known as nonspecific crossreacting antigen (NCA) and CD66c, is one of seven human CEACAM family members within the immunoglobulin superfamily. It s a glycosylphosphatidylinositol-linked immunoglobulin superfamily member that is overexpressed in a variety of human cancers, including colon, breast and lung and is associated with tumourigenesis, tumour cell adhesion, invasion and metastasis. CEACAM6 is a unique mediator of migration and invasion of drug resistant oestrogen-deprived breast cancer cells, and this protein could be an important biomarker of metastasis. CEACAM6 is expressed by granulocytes and their progenitors. It is also expressed by epithelia of various organs and is upregulated in pancreatic and colon adenocarcinomas, as well as hyperplastic polyps. Resistance to adhesion-related apoptosis in tumor cells is conferred in the condition of CEACAM6 overexpression. |
| Conjucates | APC |
| Others Formats | Unconjugated/PerCP/FITC/HRP/PE |
| Antibody Types Available | 6 |
| Immunogen | Human cell-derived rhCEACAM6 (TMPY-00971) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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