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OAT

Organic anion transporters (OATs) are the secondary/tertiary active transporter proteins that regulate anion balance in the body. They are primarily expressed in the kidney and liver and control the excretion of common drugs, toxins, and endogenous metabolites into the urine.

  • URAT1 inhibitor 7
    T775171632002-28-8
    URAT1 inhibitor 7 is a novel and potent inhibitor of the human uric acid transporter protein URAT1 (IC50:12 nM).URAT1 inhibitor 7 inhibits CYP2C9 with an IC50 of 4.2 μM.URAT1 inhibitor 7 can be used to study hyperuricemia and gout.
    • $195
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  • Lingdolinurad
    T798542088176-96-7In house
    Lingdolinurad is a uric acid transporter protein inhibitor targeting hURAT1 for the study of hyperuricemia or gout.
    • $195 TargetMol
    In Stock
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    TargetMol | Inhibitor Sale
  • Epaminurad HCl
    T27275L1198153-46-6
    Epaminurad HCl is a URAT1 inhibitor with partial inhibition of OAT1 and OAT3 (organic anion transporters).Epaminurad HCl is a pro-uric acid excretory agent used for the prevention and treatment of gout and hyperuricemia.
    • $126 TargetMol
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  • Fraxin
    T3783524-30-1
    Fraxin (Fraxoside) is a glucoside of fraxetin.
    • $32
    In Stock
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    TargetMol | Citations Cited
  • Lesinurad
    T6875878672-00-5
    Lesinurad (RDEA594) is a selective inhibitor of uric acid reabsorption which is used in combination with other agents in the therapy of gout. Lesinurad has had a limited clinical use but has not been associated with serum enzyme elevations during therapy or with instances of clinically apparent liver injury.
    • $39
    In Stock
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  • Puliginurad
    T610482013582-27-7
    Puliginurad (YL-90148) is a potent and selective inhibitor of urate transporter protein (URAT) with inhibitory effects on uric acid reabsorption.Puliginurad can be used for the prevention and treatment of hyperuricemia and gout.
    • $196
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  • Verinurad
    T39941352792-74-5
    Verinurad (RDEA3170) (RDEA3170) is an organic anion transporter URAT1 (SLC22A12) inhibitor for the treatment of gout and hyperuricemia.
    • $39
    In Stock
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  • Dotinurad
    T151601285572-51-1
    Dotinurad ((3,5-dichloro-4-hydroxyphenyl)(1,1-dioxidobenzo[d]thiazol-3(2H)-yl)methanone) is a potent agent of uricosuric (IC50: 3.6 μM for uric acid).
    • $132
    In Stock
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  • Indican
    T19866487-60-5
    Indican (Indoxyl-β-D-glucoside) is a natural protective compound that is used to protect the liver.
    • $42
    In Stock
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  • URAT1 inhibitor 1
    T132592268720-62-1
    URAT1 inhibitor 1 (1g) is an inhibitor of uric acid transporter 1 (URAT1) (IC50: 32 nM), has the potential to treat hyperuricemia associated with gout.
    • $1,620
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  • Benzarone
    T205451477-19-6
    Benzarone (Benzarona) is a potent inhibitor of human uric acid transporter 1 (URAT1, IC50 = 2.8 μM in oocyte). Benzarone lowers the level of uric acid serum.
    • $39
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