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Anti-PGC1 beta Polyclonal Antibody is a Rabbit antibody targeting PGC1 beta. Anti-PGC1 beta Polyclonal Antibody can be used in ELISA,IF,IHC-Fr,IHC-P,WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $222 | 7-10 days | |
| 100 μL | $373 | 7-10 days | |
| 200 μL | $528 | 7-10 days |
| Description | Anti-PGC1 beta Polyclonal Antibody is a Rabbit antibody targeting PGC1 beta. Anti-PGC1 beta Polyclonal Antibody can be used in ELISA,IF,IHC-Fr,IHC-P,WB. |
| Synonyms | PRGC2, PPARGC-1-beta, Ppargc1b, PPARGC1, PPAR-gamma coactivator 1-beta, PPAR gamma coactivator-1beta, PGC1β, PGC-1-related estrogen receptor alpha coactivator, PGC-1-beta, PGC-1(beta), PGC1 β, PGC1, peroxisome proliferator-activated receptor gamma, coactivator 1 beta, peroxisome proliferator-activated receptor gamma coactivator 1 beta, peroxisome proliferative activated receptor, gamma, coactivator 1, PERC |
| Ig Type | IgG |
| Reactivity | (predicted:Human,Mouse,Rat,Dog,Pig,Cow,Rabbit,GuineaPig) |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Tissue Specificity | Ubiquitous with higher expression in heart,brain and skeletal muscle. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcritional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be involved in fat oxidation and non-oxidative glucose metabolism and in the regulation of energy expenditure. Tissue specificity: Ubiquitous with higher expression in heart, brain and skeletal muscle. |
| Immunogen | KLH conjugated synthetic peptide: human PGC1 beta |
| Antigen Species | Human |
| Gene Name | PPARGC1B |
| Gene ID | |
| Protein Name | Peroxisome proliferator-activated receptor gamma coactivator 1-beta |
| Uniprot ID | |
| Biology Area | Diabetes associated,Metabolism,Co-activators/co-repressors,Estrogen,Energy Metabolism,Fatty acids,Mitochondrial markers,Fatty acid oxidation,Diabetes,Heart disease,Energy Metabolism,Mitochondrial |
| Function | Plays a role of stimulator of transcription factors andnuclear receptors activities. Activates transcritional activity ofestrogen receptor alpha, nuclear respiratory factor 1 (NRF1) andglucocorticoid receptor in the presence of glucocorticoids. Mayplay a role in constitutive non-adrenergic-mediated mitochondrialbiogenesis as suggested by increased basal oxygen consumption andmitochondrial number when overexpressed. May be involved in fatoxidation and non-oxidative glucose metabolism and in theregulation of energy expenditure. |
| Molecular Weight | Theoretical: 113 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |

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