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Azido-PEG3-O-NHS ester, a PEG-based linker for PROTACs, connects two essential ligands crucial for forming PROTAC molecules and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Azido-PEG3-O-NHS ester, a PEG-based linker for PROTACs, connects two essential ligands crucial for forming PROTAC molecules and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs comprise two distinct ligands linked together; one targets an E3 ubiquitin ligase, and the other binds to the target protein. They utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 360.32 |
Formula | C13H20N4O8 |
Cas No. | 2110448-98-9 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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