Grazoprevir potassium salt

Name: Grazoprevir potassium salt
Brand: TargetMol
SKU: T19948
Rating: 4.5 (1 reviews)

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Catalog No. T19948Cas No. 1206524-86-8

Alias MK-5172 potassium salt, MK 5172 potassium, Grazoprevir potassium

Grazoprevir is a drug approved for the treatment of hepatitis C. Grazoprevir is a second-generation hepatitis C virus protease inhibitor acting at the NS3/4a protease targets.

Grazoprevir potassium salt

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Catalog No. T19948Alias MK-5172 potassium salt, MK 5172 potassium, Grazoprevir potassiumCas No. 1206524-86-8

Grazoprevir is a drug approved for the treatment of hepatitis C. Grazoprevir is a second-generation hepatitis C virus protease inhibitor acting at the NS3/4a protease targets.

Pack Size	Price	Availability	Quantity
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100 mg	Inquiry	Backorder

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Product Introduction

Bioactivity

Description	Grazoprevir is a drug approved for the treatment of hepatitis C. Grazoprevir is a second-generation hepatitis C virus protease inhibitor acting at the NS3/4a protease targets.
Targets&IC50	GT3a:0.90±0.2 nM (Ki), GT2b:0.15±0.06 nM (Ki), GT1b:0.01±<0.01 nM (Ki), GT2a:0.08±0.02 nM (Ki), GT1a:0.01±0.01 nM (Ki)
Synonyms	MK-5172 potassium salt, MK 5172 potassium, Grazoprevir potassium

Chemical Properties

Molecular Weight	805
Formula	C₃₈H₄₉KN₆O₉S
Cas No.	1206524-86-8
Relative Density.	no data available

Storage & Solubility Information

Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Solubility Information	DMSO: Soluble

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc