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Scopine hydrochloride

Name: Scopine hydrochloride
Brand: TargetMol
SKU: T6663
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T6663Cas No. 85700-55-6

Alias Scopine HCl, 6,7-Epoxytropine hydrochloride

Scopine hydrochloride is a brain-targeting scopolamine metabolite that enhances intracerebral exposure and anti-glioblastoma activity of chlorambucil, applicable for targeted treatment of brain gliomas.

Scopine hydrochloride

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Purity: 98.69%

Catalog No. T6663Alias Scopine HCl, 6,7-Epoxytropine hydrochlorideCas No. 85700-55-6

Pack Size	Price	USA Warehouse	Global Warehouse
2 mg	$30	-	In Stock
5 mg	$44	-	In Stock
10 mg	$61	-	In Stock
25 mg	$98	-	In Stock
50 mg	$139	-	In Stock
100 mg	$198	-	In Stock
1 mL x 10 mM (in DMSO)	$45	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:98.69%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Scopine hydrochloride is a brain-targeting scopolamine metabolite that enhances intracerebral exposure and anti-glioblastoma activity of chlorambucil, applicable for targeted treatment of brain gliomas.
Synonyms	Scopine HCl, 6,7-Epoxytropine hydrochloride

Chemical Properties

Molecular Weight	191.66
Formula	C₈H₁₃NO₂·HCl
Cas No.	85700-55-6
Smiles	CN1[C@@]2([C@]3([C@](O3)([C@]1(C[C@@H](O)C2)[H])[H])[H])[H].Cl
Relative Density.	no data available

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 20 mg/mL (104.35 mM), Sonication is recommended.

H2O: ≥ 80 mg/mL, Sonication is recommended.

Ethanol: <1 mg/mL (<1 mM)

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween-80+45% Saline: 2 mg/mL (10.44 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	5.2176 mL	26.0879 mL	52.1757 mL	260.8786 mL

DMSO

	1mg	5mg	10mg	50mg
5 mM	1.0435 mL	5.2176 mL	10.4351 mL	52.1757 mL
10 mM	0.5218 mL	2.6088 mL	5.2176 mL	26.0879 mL
20 mM	0.2609 mL	1.3044 mL	2.6088 mL	13.0439 mL
50 mM	0.1044 mL	0.5218 mL	1.0435 mL	5.2176 mL
100 mM	0.0522 mL	0.2609 mL	0.5218 mL	2.6088 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc