T33452 |
ML192
|
460331-61-7
|
99.79%
|
|
ML192 (CID1434953) is a selective GPR55 ligand antagonist. ML192 is an inhibitor that inhibits β-arrestin transport, ERK1/2 phosphorylation, and PKCβII transloca...
|
TP2112L |
TC14012 acetate
|
TP2112L
|
99.71%
|
|
TC14012 acetate is a serum-stable derivative of T140 which is a selective and peptidomimetic CXCR4 antagonist with an IC50 of 19.3 nM. TC14012 is also a potent C...
|
TP1922L1 |
ELA-11 (human) acetate(1784687-32-6 free base)
|
TP1922L1
|
99.53%
|
|
ELA-11 (human) acetate high affinity apelin receptor agonist (Ki = 14 nM). Bioactive fragment of ELA-32. Inhibits forskolin-induced cAMP production and stimulate...
|
T13324 |
VUF11207 fumarate
|
1785665-61-3
|
99.5%
|
|
VUF11207 fumarate is an agonist of CXCR7 and a high-potency ligand of CXCR7 (pKi: 8.1).
|
T41231 |
GP 1a
|
511532-96-0
|
99.44%
|
|
GP 1a is a potent agonist of cannabinoid receptor 2 (CB2) (EC50=7.1), as shown in cAMP, GTPγS and β-arrestin recruitment assays. GP 1a is approximately 30-fold m...
|
TP2158L1 |
TRV-120027 acetate (1234510-46-3 free base)
|
1824712-70-0
|
99.34%
|
|
TRV-120027 acetate is a β-arrestin-1-biased agonist of the angiotensin II receptor type 1 (AT1 receptor) and engages -arrestins while blocking G-protein signali...
|
T77673 |
7-FluorotryptaMine HCl
|
159730-09-3
|
98.06%
|
|
7-FluorotryptaMine HCl is a potent aromatic monoamine GPRC5A agonist that induces GPRC5A-mediated β-arrestin recruitment.7-FluorotryptaMine HCl can be used to st...
|
T4390 |
ML221
|
877636-42-5
|
97.74%
|
|
ML221 is a potent apelin /APJ functional antagonist, inhibiting apelin-13-mediated activation of APJ, with IC50s of 0.70 μM in the cAMP assay, and 1.75 μM in the...
|
TP2158 |
TRV-120027 TFA
|
TP2158
|
97.45%
|
|
TRV120027 TFA is a β-arrestin-1-biased agonist of the angiotensin II receptor type 1 (AT1R) and engages ß-arrestins while blocking G-protein signaling.
|
T23434 |
GPR35 agonist 2
|
494191-73-0
|
97.18%
|
|
GPR35 agonist 2 (TC-G 1001) is a potent GPR35 agonist.The EC50 values of GPR35 agonist 2 in the β-arrestin and Ca2+ release assays were 26 and 3.2 nM, respective...
|
TP1923L1 |
ELA-14(human) acetate
|
TP1923L1
|
98%
|
|
ELA-14(human) acetate is a fragment of ELA that binds to APJ, activates the Gαi1 and β-arrestin-2 signaling pathways, and induces receptor internalization simila...
|
T8423 |
ML417
|
1386162-69-1
|
98%
|
|
ML417 is a selective and brain penetrant agonist of D3 Dopamine (EC50 : 38 nM).
|
T23866 |
CCX777
|
1226686-36-7
|
98%
|
|
CCX777 is a partial agonist recruited to ACKR3 by β-arrestin-2 and is used in cancer research.
|