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Arrestin

Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T33452 ML192 460331-61-7 99.79%
ML192
ML192 (CID1434953) is a selective GPR55 ligand antagonist. ML192 is an inhibitor that inhibits β-arrestin transport, ERK1/2 phosphorylation, and PKCβII transloca...
TP2112L TC14012 acetate TP2112L 99.71%
TC14012 acetate
TC14012 acetate is a serum-stable derivative of T140 which is a selective and peptidomimetic CXCR4 antagonist with an IC50 of 19.3 nM. TC14012 is also a potent C...
TP1922L1 ELA-11 (human) acetate(1784687-32-6 free base) TP1922L1 99.53%
ELA-11 (human) acetate(1784687-32-6 free base)
ELA-11 (human) acetate high affinity apelin receptor agonist (Ki = 14 nM). Bioactive fragment of ELA-32. Inhibits forskolin-induced cAMP production and stimulate...
T13324 VUF11207 fumarate 1785665-61-3 99.5%
VUF11207 fumarate
VUF11207 fumarate is an agonist of CXCR7 and a high-potency ligand of CXCR7 (pKi: 8.1).
T41231 GP 1a 511532-96-0 99.44%
GP 1a
GP 1a is a potent agonist of cannabinoid receptor 2 (CB2) (EC50=7.1), as shown in cAMP, GTPγS and β-arrestin recruitment assays. GP 1a is approximately 30-fold m...
TP2158L1 TRV-120027 acetate (1234510-46-3 free base) 1824712-70-0 99.34%
TRV-120027 acetate (1234510-46-3 free base)
TRV-120027 acetate is a β-arrestin-1-biased agonist of the angiotensin II receptor type 1 (AT1 receptor) and engages -arrestins while blocking G-protein signali...
T77673 7-FluorotryptaMine HCl 159730-09-3 98.06%
7-FluorotryptaMine HCl
7-FluorotryptaMine HCl is a potent aromatic monoamine GPRC5A agonist that induces GPRC5A-mediated β-arrestin recruitment.7-FluorotryptaMine HCl can be used to st...
T4390 ML221 877636-42-5 97.74%
ML221
ML221 is a potent apelin /APJ functional antagonist, inhibiting apelin-13-mediated activation of APJ, with IC50s of 0.70 μM in the cAMP assay, and 1.75 μM in the...
TP2158 TRV-120027 TFA TP2158 97.45%
TRV-120027 TFA
TRV120027 TFA is a β-arrestin-1-biased agonist of the angiotensin II receptor type 1 (AT1R) and engages ß-arrestins while blocking G-protein signaling.
T23434 GPR35 agonist 2 494191-73-0 97.18%
GPR35 agonist 2
GPR35 agonist 2 (TC-G 1001) is a potent GPR35 agonist.The EC50 values of GPR35 agonist 2 in the β-arrestin and Ca2+ release assays were 26 and 3.2 nM, respective...
TP1923L1 ELA-14(human) acetate TP1923L1 98%
ELA-14(human) acetate
ELA-14(human) acetate is a fragment of ELA that binds to APJ, activates the Gαi1 and β-arrestin-2 signaling pathways, and induces receptor internalization simila...
T8423 ML417 1386162-69-1 98%
ML417
ML417 is a selective and brain penetrant agonist of D3 Dopamine (EC50 : 38 nM).
T23866 CCX777 1226686-36-7 98%
CCX777
CCX777 is a partial agonist recruited to ACKR3 by β-arrestin-2 and is used in cancer research.
ML192
T33452
ML192 (CID1434953) is a selective GPR55 ligand antagonist. ML192 is an inhibitor that inhibits β-arrestin transport, ERK1/2 phosphorylation, and PKCβII transloca...
TC14012 acetate
TP2112L
TC14012 acetate is a serum-stable derivative of T140 which is a selective and peptidomimetic CXCR4 antagonist with an IC50 of 19.3 nM. TC14012 is also a potent C...
ELA-11 (human) acetate(1784687-32-6 free base)
TP1922L1
ELA-11 (human) acetate high affinity apelin receptor agonist (Ki = 14 nM). Bioactive fragment of ELA-32. Inhibits forskolin-induced cAMP production and stimulate...
VUF11207 fumarate
T13324
VUF11207 fumarate is an agonist of CXCR7 and a high-potency ligand of CXCR7 (pKi: 8.1).
GP 1a
T41231
GP 1a is a potent agonist of cannabinoid receptor 2 (CB2) (EC50=7.1), as shown in cAMP, GTPγS and β-arrestin recruitment assays. GP 1a is approximately 30-fold m...
TRV-120027 acetate (1234510-46-3 free base)
TP2158L1
TRV-120027 acetate is a β-arrestin-1-biased agonist of the angiotensin II receptor type 1 (AT1 receptor) and engages -arrestins while blocking G-protein signali...
7-FluorotryptaMine HCl
T77673
7-FluorotryptaMine HCl is a potent aromatic monoamine GPRC5A agonist that induces GPRC5A-mediated β-arrestin recruitment.7-FluorotryptaMine HCl can be used to st...
ML221
T4390
ML221 is a potent apelin /APJ functional antagonist, inhibiting apelin-13-mediated activation of APJ, with IC50s of 0.70 μM in the cAMP assay, and 1.75 μM in the...
TRV-120027 TFA
TP2158
TRV120027 TFA is a β-arrestin-1-biased agonist of the angiotensin II receptor type 1 (AT1R) and engages ß-arrestins while blocking G-protein signaling.
GPR35 agonist 2
T23434
GPR35 agonist 2 (TC-G 1001) is a potent GPR35 agonist.The EC50 values of GPR35 agonist 2 in the β-arrestin and Ca2+ release assays were 26 and 3.2 nM, respective...
ELA-14(human) acetate
TP1923L1
ELA-14(human) acetate is a fragment of ELA that binds to APJ, activates the Gαi1 and β-arrestin-2 signaling pathways, and induces receptor internalization simila...
ML417
T8423
ML417 is a selective and brain penetrant agonist of D3 Dopamine (EC50 : 38 nM).
CCX777
T23866
CCX777 is a partial agonist recruited to ACKR3 by β-arrestin-2 and is used in cancer research.
TargetMol