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Substance P (3-11)

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Catalog No. T81078Cas No. 51165-11-8

Substance P (3-11), an SP fragment peptide capable of crossing the blood-brain barrier (BBB), induces contraction in guinea pig ileum and facilitates chemotaxis in human monocytes [1] [2] [5].

Substance P (3-11)

Substance P (3-11)

😃Good
Catalog No. T81078Cas No. 51165-11-8
Substance P (3-11), an SP fragment peptide capable of crossing the blood-brain barrier (BBB), induces contraction in guinea pig ileum and facilitates chemotaxis in human monocytes [1] [2] [5].
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Product Introduction

Bioactivity
Description
Substance P (3-11), an SP fragment peptide capable of crossing the blood-brain barrier (BBB), induces contraction in guinea pig ileum and facilitates chemotaxis in human monocytes [1] [2] [5].
In vitro
Substance P (3-11) can permeate the BBMEC monolayer with a penetration rate of 1.
In vivo
Substance P (3-11) (30 nmol/kg, intravenous infusion) increases histamine levels in rat plasma [4].
Chemical Properties
Molecular Weight1094.33
FormulaC52H79N13O11S
Cas No.51165-11-8
SmilesC(N[C@H](C(N[C@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC2=CC=CC=C2)C(NCC(N[C@H](C(N[C@@H](CCSC)C(N)=O)=O)CC(C)C)=O)=O)=O)=O)CCC(N)=O)=O)CCC(N)=O)(=O)[C@H]3N(C([C@H](CCCCN)N)=O)CCC3
Sequence ShortKPQQFFGLM-NH2
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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