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Substance P (3-11)

Name: Substance P (3-11)
Brand: TargetMol
SKU: T81078
Rating: 4.5 (1 reviews)

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Catalog No. T81078Cas No. 51165-11-8

Substance P (3-11), an SP fragment peptide capable of crossing the blood-brain barrier (BBB), induces contraction in guinea pig ileum and facilitates chemotaxis in human monocytes [1] [2] [5].

Substance P (3-11)

😃Good

Catalog No. T81078Cas No. 51165-11-8

Substance P (3-11), an SP fragment peptide capable of crossing the blood-brain barrier (BBB), induces contraction in guinea pig ileum and facilitates chemotaxis in human monocytes [1] [2] [5].

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Product Introduction

Bioactivity

Description	Substance P (3-11), an SP fragment peptide capable of crossing the blood-brain barrier (BBB), induces contraction in guinea pig ileum and facilitates chemotaxis in human monocytes [1] [2] [5].
In vitro	Substance P (3-11) can permeate the BBMEC monolayer with a penetration rate of 1.
In vivo	Substance P (3-11) (30 nmol/kg, intravenous infusion) increases histamine levels in rat plasma [4].

Chemical Properties

Molecular Weight	1094.33
Formula	C₅₂H₇₉N₁₃O₁₁S
Cas No.	51165-11-8
Sequence Short	KPQQFFGLM-NH2

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

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