This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.
This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.
20-HC-Me-Pyrrolidine
Catalog No. T62380
20-HC-Me-Pyrrolidine was A potent inhibitor of Aster protein, with IC50 values of 0.11 μM, 0.06 μM and 0.71 μM for Aster A, Aster B and Aster C, respectively. 20-HC-Me-Pyrrolidine prevents Aster protein from binding and transferring cholesterol and inhibits the movement of low-density lipoprotein (LDL) cholesterol into the endoplasmic reticulum (ER).
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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.
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Biological Description
Chemical Properties
Storage
& Solubility Information
Description
20-HC-Me-Pyrrolidine was A potent inhibitor of Aster protein, with IC50 values of 0.11 μM, 0.06 μM and 0.71 μM for Aster A, Aster B and Aster C, respectively. 20-HC-Me-Pyrrolidine prevents Aster protein from binding and transferring cholesterol and inhibits the movement of low-density lipoprotein (LDL) cholesterol into the endoplasmic reticulum (ER).
Molecular Weight
429.68
Formula
C28H47NO2
Storage
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Dose Conversion
You can also refer to dose conversion for different animals.
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Method for preparing DMSO master liquid: mg
drug pre-dissolved in μL DMSO (Master liquid concentration
mg/mL),
Method for preparing in vivo formulation:Take μL
DMSO master liquid, next add μL PEG300, mix and clarify, next add μL
Tween 80,mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation:Take μL
DMSO master liquid, next add μL Corn oil,mix and clarify.
Note:
Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.