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20-HC-Me-Pyrrolidine is a potent Aster protein inhibitor with IC50=0.06~0.71 μm for Aster-A, Aster-B, and Aster-C that blocks the ability of Aster proteins to bind and transfer cholesterol, including inhibiting the movement of LDL cholesterol to the endoplasmic reticulum.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $201 | In Stock | |
5 mg | $503 | In Stock | |
10 mg | $811 | In Stock | |
25 mg | $1,180 | In Stock | |
50 mg | $1,630 | In Stock | |
100 mg | $2,190 | In Stock | |
200 mg | $2,960 | In Stock |
Description | 20-HC-Me-Pyrrolidine is a potent Aster protein inhibitor with IC50=0.06~0.71 μm for Aster-A, Aster-B, and Aster-C that blocks the ability of Aster proteins to bind and transfer cholesterol, including inhibiting the movement of LDL cholesterol to the endoplasmic reticulum. |
Targets&IC50 | Aster-A:0.87 μM, Aster-B:0.21 μM, Aster-C:1.41 μM |
In vitro | 20-HC-Me-Pyrrolidine is a potent inhibitor of Aster proteins, with IC₅₀ values of 0.87 μM for Aster-A, 0.21 μM for Aster-B, and 1.41 μM for Aster-C [1]. |
Molecular Weight | 429.68 |
Formula | C28H47NO2 |
Smiles | C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2C(C)(C)O)CC=C4[C@@]3(CC[C@@H](C4)OCCN5CCCC5)C |
Color | Yellow |
Appearance | Solid |
Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||
Solubility Information | DMSO: 13.15 mg/mL (30.6 mM), Sonication is recommended. ![]() | |||||||||||||||||||||||||
In Vivo Formulation | 50% PEG300+50% Saline: 2 mg/mL (4.65 mM), Suspension. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.![]() | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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