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CD25/IL2R alpha Protein, Human, Recombinant (N-His)
(Synonyms: TAC-antigen, Tac antigen, soluble IL-2 receptor, IL-2Rα, IL2RA, CD25 antigen) Copy Product InfoSynonyms: TAC-antigen, Tac antigen, soluble IL-2 receptor, IL-2Rα, IL2RA, CD25 antigen
Catalog No. TMPS-00075 Copy Product Info
CD25/IL2R alpha Protein, Human, Recombinant (N-His) is expressed in HEK293 Cells. The accession number is P01589.
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $71 | 7-10 days | 7-10 days | |
| 10 µg | $113 | 7-10 days | 7-10 days | |
| 20 µg | $178 | 7-10 days | 7-10 days | |
| 50 µg | $339 | 7-10 days | 7-10 days | |
| 100 µg | $548 | 7-10 days | 7-10 days | |
| 200 µg | $898 | 7-10 days | 7-10 days | |
| 500 µg | $1,720 | 7-10 days | 7-10 days | |
| 1 mg | $2,820 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Determined by its ability to increase the proliferation effect of IL-2 in murine CTLL-2 cells. In the presence of 1.0 ng/ml of recombinant IL-2, ED 50 for this effect is < 1.5 µg/ml. |
| Description | CD25/IL2R alpha Protein, Human, Recombinant (N-His) is expressed in HEK293 Cells. The accession number is P01589. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | His |
| Accession Number | P01589 |
| Construction | Glu22-Cys213 |
| Protein Purity | > 95% as determined by SDS-PAGE; > 95% as determined by HPLC |
| Endotoxin | < 0.2 EU/μg of protein as determined by the LAL method. |
| Formulation | Lyophilized from a 0.2 μm filtered solution in PBS. |
| Reconstitution | Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | TAC-antigen, Tac antigen, soluble IL-2 receptor, IL-2Rα, IL2RA, CD25 antigen |
| Research Background | Interleukin-2 receptor (IL-2R) is a heterotrimeric protein expressed on the surface of certain immune cells, such as lymphocytes, that binds and responds to the cytokine IL-2. The IL-2R is made up of 3 subunits - alpha (α), beta (β) and gamma (γ). The α and β chains are involved in binding IL-2, while signal transduction following cytokine interaction is carried out by the γ-chain, along with the β subunit. The β and γ chains of the IL-2R are members of the type I cytokine receptor family. IL-2R has a high binding affinity to IL-2 and is expressed by antigen-activated T lymphocytes (T cells). IL-2 Rα is also known as CD25, p55, and Tac (activated T cell) antigen. |
| Molecular Weight | ~42 kDa (Reducing conditions) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles. |
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Related Tags: CD25/IL2R alpha Protein, Human, Recombinant (N-His) chemical structure | CD25/IL2R alpha Protein, Human, Recombinant (N-His) molecular weight
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