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Anti-Nucleoside phosphorylase/PNP Antibody (7S883) is a Rabbit antibody targeting Nucleoside phosphorylase/PNP. Anti-Nucleoside phosphorylase/PNP Antibody (7S883) can be used in IHC-P.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $269 | 7-10 days |
Description | Antibody Type: Rabbit Monoclonal Application: IHC-P Reactivity: Human |
Alias | purine nucleoside phosphorylase, PUNP, PRO1837, NP |
Ig Type | Rabbit IgG |
Clone | 7S883 |
Reactivity | Human |
Verified Activity | 1. Immunochemical staining of human PNP in human placenta with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human PNP in human kidney with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). |
Application | IHC-P |
Recommended Dose | IHC-P: 1:100-1:500 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human PNP (rh PNP; TMPY-02279; P00491; Met1-Ser289). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Purine nucleoside phosphorylase (PNP) is a purine-metabolizing enzyme that catalyzes the reversible phosphorolysis of 6-oxypurine (deoxy)nucleosides to their respective bases and (deoxy)ribose-1-phosphate. It is a key enzyme in the purine salvage pathway of mammalian cells. Purine nucleoside phosphorylase is a transferase that catalyzes the addition of phosphate and removal of a purine base from guanosine and similar nucleosides.PNP defects result in metabolic abnormalities and fatal T cell immunodeficiency. Purine nucleoside phosphorylase (PNP) is a target for leukemia, gout, and autoimmune disorders. |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein: Human PNP protein (TMPY-02279) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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