CCR2b Protein-VLP, Human, Recombinant

Catalog No. TMPK-00879 Copy Product Info

The chemokine (C-C motif) receptor 2B (CCR2B) is one of the two isoforms of the receptor for monocyte chemoattractant protein-1 (CCL2), the major chemoattractant for monocytes, involved in an array of chronic inflammatory diseases. The actin-binding protein filamin A (FLNa) as a protein that associates with the carboxyl-terminal tail of CCR2B. FLNa emerges as an important protein for controlling the internalization and spatial localization of the CCR2B receptor in different dynamic membrane structures.

CCR2b Protein-VLP, Human, Recombinant

Catalog No. TMPK-00879

Copy Product Info

Pack Size	Price	USA Stock	Global Stock
5 μg	$172	4-6 weeks	4-6 weeks
10 μg	$286	4-6 weeks	4-6 weeks
20 μg	$478	4-6 weeks	4-6 weeks
50 μg	$957	4-6 weeks	4-6 weeks
100 μg	$1,620	4-6 weeks	4-6 weeks
200 μg	$2,930	4-6 weeks	4-6 weeks
500 μg	$6,520	4-6 weeks	4-6 weeks

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In stock · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

For research use only—not for human use. No sales to individuals. Use as intended only.

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Biological Activity	Immobilized Human CCR2b VLP at 5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-CCR2b Antibody, hFc Tag with the EC50 of 12.0ng/ml determined by ELISA.
Description	The chemokine (C-C motif) receptor 2B (CCR2B) is one of the two isoforms of the receptor for monocyte chemoattractant protein-1 (CCL2), the major chemoattractant for monocytes, involved in an array of chronic inflammatory diseases. The actin-binding protein filamin A (FLNa) as a protein that associates with the carboxyl-terminal tail of CCR2B. FLNa emerges as an important protein for controlling the internalization and spatial localization of the CCR2B receptor in different dynamic membrane structures.
Species	Human
Expression System	HEK293 Cells
Accession Number	P41597-2
Synonyms	MCP-1-R,CMKBR2,CCR-2,CCR2,C-C CKR-2
Construction	Met1-Leu360
Protein Purity	> 95% as determined by HPLC
Molecular Weight	42.9kDa (predicted)
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Supplied as 0.22 μm filtered solution in PBS (pH 7.4).Notice: If you need it for immunization, Do Not use any adjuvant.
Stability & Storage	It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	Proteins are shipped with blue ice.
Research Background	The chemokine (C-C motif) receptor 2B (CCR2B) is one of the two isoforms of the receptor for monocyte chemoattractant protein-1 (CCL2), the major chemoattractant for monocytes, involved in an array of chronic inflammatory diseases. The actin-binding protein filamin A (FLNa) as a protein that associates with the carboxyl-terminal tail of CCR2B. FLNa emerges as an important protein for controlling the internalization and spatial localization of the CCR2B receptor in different dynamic membrane structures.

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Keywords

CMKBR-2 CMKBR 2 CCR 2