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CDCP1 Protein, Human, Recombinant (aa 30-368, His)

Catalog No. TMPK-01183
Synonyms: CDCP1, PRO5773, TRASK, CD318, UNQ2486, SIMA135

Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss of CDCP1 have been observed in the same cancer types to promote metastatic progression.

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CDCP1 Protein, Human, Recombinant (aa 30-368, His)
Pack Size Availability Price/USD Quantity
100 μg 5 days $ 814.00
500 μg 5 days $ 3,250.00
1 mg 5 days $ 5,440.00
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Biological Description
Technical Params
Product Properties
References and Literature
Description Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss of CDCP1 have been observed in the same cancer types to promote metastatic progression.
Species Human
Expression System HEK293
Tag C-His
Accession Number Q9H5V8-1
Synonyms CDCP1, PRO5773, TRASK, CD318, UNQ2486, SIMA135
Construction Recombinant Human CDCP1 (30-368) Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Phe30-Arg368.[Accession |Q9H5V8-1]
Protein Purity > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight The protein has a predicted MW of 39.03 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
Endotoxin Less than 1EU per μg by the LAL method.
Formulation Lyophilized from 0.22μm filtered solution in 20mM PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability & Storage

-20 to -80°C for 12 months as supplied from date of receipt. -20 to -80°C for 3-6 months in unopened state after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Research Background Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss of CDCP1 have been observed in the same cancer types to promote metastatic progression.

References and Literature

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Keywords

CDCP1 Protein, Human, Recombinant (aa 30-368, His) SIMA 135 PRO 5773 CDCP1 PRO5773 CDCP-1 SIMA-135 UNQ 2486 CDCP 1 TRASK PRO-5773 CD-318 CD318 CD 318 UNQ-2486 UNQ2486 SIMA135 recombinant recombinant-proteins proteins protein

 

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