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Paclitaxel-d5
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Catalog No. TMID-0018Cas No. 1129540-33-5
Paclitaxel-d5 is the deuterated analog of Paclitaxel, a diterpenoid natural product originally isolated from Pacific yew bark. Paclitaxel-d5 maintains the parent compound’s ability to stabilize microtubules and induce mitotic arrest leading to apoptosis, and it is widely used as an internal standard in analytical assays and mechanistic drug studies.
Paclitaxel-d5
😃Good
Catalog No. TMID-0018Cas No. 1129540-33-5
Paclitaxel-d5 is the deuterated analog of Paclitaxel, a diterpenoid natural product originally isolated from Pacific yew bark. Paclitaxel-d5 maintains the parent compound’s ability to stabilize microtubules and induce mitotic arrest leading to apoptosis, and it is widely used as an internal standard in analytical assays and mechanistic drug studies.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 500 μg | $228 | - | In Stock | |
| 1 mg | $372 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Chemical Properties
| Description | Paclitaxel-d5 is the deuterated analog of Paclitaxel, a diterpenoid natural product originally isolated from Pacific yew bark. Paclitaxel-d5 maintains the parent compound’s ability to stabilize microtubules and induce mitotic arrest leading to apoptosis, and it is widely used as an internal standard in analytical assays and mechanistic drug studies. |
| Molecular Weight | 858.94 |
| Formula | C47H46D5NO14 |
| Cas No. | 1129540-33-5 |
| Smiles | O(C(C)=O)[C@]12[C@]3([C@H](OC(=O)C4=CC=CC=C4)[C@@]5(O)C(C)(C)C([C@@H](OC(C)=O)C(=O)[C@]3(C)[C@@H](O)C[C@]1(OC2)[H])=C(C)[C@@H](OC([C@@H]([C@@H](NC(=O)C6=C(C(=C(C(=C6[2H])[2H])[2H])[2H])[2H])C7=CC=CC=C7)O)=O)C5)[H] |
| Color | White |
| Appearance | Solid |
Storage & Solubility Information
| Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO: ≥ 4 mg/mL, Sonication is recommended. Ethanol: ≥ 1.2 mg/mL, Sonication is recommended. DMF: ≥ 4 mg/mL, Sonication is recommended. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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