Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-Caspase-14 Antibody (6X805)

😃Good
Catalog No. TMAY-02114
Alias caspase 14, apoptosis-related cysteine peptidase, ARCI12

Anti-Caspase-14 Antibody (6X805) is a Rabbit antibody targeting Caspase-14. Anti-Caspase-14 Antibody (6X805) can be used in IHC-P,ICC/IF.

Anti-Caspase-14 Antibody (6X805)

Anti-Caspase-14 Antibody (6X805)

😃Good
Catalog No. TMAY-02114Alias caspase 14, apoptosis-related cysteine peptidase, ARCI12
Anti-Caspase-14 Antibody (6X805) is a Rabbit antibody targeting Caspase-14. Anti-Caspase-14 Antibody (6X805) can be used in IHC-P,ICC/IF.
Pack SizePriceAvailabilityQuantity
100 μL$268 7-10 days
Bulk & Custom
Add to Cart
Questions
View More
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
Anti-Caspase-14 Antibody (6X805) is a Rabbit antibody targeting Caspase-14. Anti-Caspase-14 Antibody (6X805) can be used in IHC-P,ICC/IF.
Aliascaspase 14, apoptosis-related cysteine peptidase, ARCI12
Ig Type
Monoclonal Rabbit IgG
Clone
6X805
Reactivity
Human
Verified Activity
1. Immunofluorescence staining of Human CSAP14 in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 1% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human CASP14 monoclonal antibody (1:60) at 37°C 1 hour. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue). Positive staining was localized to cytoplasm and Nucleus.

2. Immunochemical staining of human CASP14 in human skin with rabbit monoclonal antibody (1:300, formalin-fixed paraffin embedded sections).
Application
IHC-P,ICC/IF
Recommended Dose
IHC-P: 1:100-1:500; ICC-IF: 1:20-1:100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human Caspase-14 / CASP14 (rh Caspase-14 / CASP14; TMPY-01824; NP_036246.1; Ser2-Gln242).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundCaspase 14 is a member of the caspase family. Caspases are a kind of cysteine proteinase consisting of a prodomain plus large and small catalytic subunits, that play a central role in cell apoptosis. Caspase 14 possesses an unusually short prodomain and is highly expressed in embryonic tissues but absent from most of the adult tissues except for the skin, which suggests a role in ontogenesis and skin physiology. Unlike the other short prodomain caspases(caspase-3, caspase-6, and caspase-7), Caspase 14 was not processed by multiple death stimuli including activation of members of the tumor necrosis factor receptor family and expression of proapaptotic members of the bcl-2 family. Caspase 14 has been described to be processed and activated by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may take part in keratinocyte terminal differentiation, which is essential for the skin barrier.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human Caspase-14 / CASP14 protein (TMPY-01824)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

Sci Citations

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy Anti-Caspase-14 Antibody (6X805) | purchase Anti-Caspase-14 Antibody (6X805) | Anti-Caspase-14 Antibody (6X805) cost | order Anti-Caspase-14 Antibody (6X805)