CCL21 Protein, Human, Recombinant

CCL21 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 12.3 kDa and the accession number is O00585.

Pack Size	Availability	Price/USD	Quantity
50 μg	5 days	$ 618.00
1 mg	5 days	$ 4,020.00

Pack Size

Availability

Price/USD

Quantity

50 μg

5 days

$ 618.00

1 mg

5 days

$ 4,020.00

Description

CCL21 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 12.3 kDa and the accession number is O00585.

Species	Human
Expression System	Baculovirus Insect Cells
Tag	Tag Free
Accession Number	O00585
Synonyms	CKb9, MGC34555, TCA4, ECL, 6Ckine, SLC, SCYA21, RP11-195F19.22-001, chemokine (C-C motif) ligand 21
Construction	The Human CCL21 (O00585) (Met 1-Pro 134) was expressed and purified.
Protein Purity	> 98 % as determined by SDS-PAGE
Molecular Weight	12.3 kDa (predicted)

Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing 40 mM Tris, 0.3 M NaCl, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice.
Research Background	Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved locations in order to form their 3-dimensional shape. Some of the chemokines are considered pro-inflammatory which can be induced to recruit cells of the immune system to a site of infection during an immune response, while others are considered homeostatic and are implied in controlling the migration of cells during normal processes of tissue maintenance and development. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands-1 to 28. Chemokine ligand 21(CCL21), also known as 6Ckine, exodus-2, and secondary lymphoid-tissue chemokine(SLC), is a small cytokine belonging to the C-C chemokine family. CCL21 takes its name 6Ckine for its consititutively six conserved cysteine residues but not four cysteines typical to chemokines. CCL21 has function in ininducing vigorous calcium migrations and chemotactic responses.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy