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Anti-CD8 alpha Antibody (7D448)
😃Good
Catalog No. TMAY-01410
Alias p32 186910, p32, MAL, Leu-2, Leu2, CD8a molecule, CD8 α, CD8 alpha, CD8
Anti-CD8 alpha Antibody (7D448) is a Rabbit antibody targeting CD8 alpha. Anti-CD8 alpha Antibody (7D448) can be used in IHC-P.
Anti-CD8 alpha Antibody (7D448)
Anti-CD8 alpha Antibody (7D448)
😃Good
Catalog No. TMAY-01410Alias p32 186910, p32, MAL, Leu-2, Leu2, CD8a molecule, CD8 α, CD8 alpha, CD8
Anti-CD8 alpha Antibody (7D448) is a Rabbit antibody targeting CD8 alpha. Anti-CD8 alpha Antibody (7D448) can be used in IHC-P.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $268 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: IHC-P Reactivity: Human, Ferret |
| Alias | p32 186910, p32, MAL, Leu-2, Leu2, CD8a molecule, CD8 α, CD8 alpha, CD8 |
| Ig Type | Rabbit IgG |
| Clone | 7D448 |
| Reactivity | Human, Ferret |
| Verified Activity | 1. Immunochemical staining CD8a in human lymph node with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 2. Immunochemical staining CD8A in Ferret spleen with rabbit monoclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections. |
| Application | IHC-P |
| Recommended Dose | IHC-P: 1:100-1:500 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD8a / Lyt2 (rh CD8a / Lyt2; NP_001759.3Met1-Asp182). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | T-cell surface glycoprotein CD8 alpha chain, also known as CD8a, is a single-pass type I membrane protein. The CD8 glycoprotein is expressed by thymocytes, mature T cells and natural killer (NK) cells and has been implicated in the recognition of monomorphic determinants on major histocompatibility complex (MHC) Class I antigens, and in signal transduction during the course of T-cell activation. Both human and rodent CD8 antigens are comprised of two distinct polypeptide chains, alpha and beta. The Ig domains of CD8 alpha are involved in controlling the ability of CD8 to be expressed. Mutation of B- and F-strand cysteine residues in CD8 alpha reduced the ability of the protein to fold properly and, therefore, to be expressed. Defects in CD8A are a cause of familial CD8 deficiency. Familial CD8 deficiency is a novel autosomal recessive immunologic defect characterized by absence of CD8+ cells, leading to recurrent bacterial infections. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human CD8a / Lyt2 protein |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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