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Anti-USP7 Antibody (8N914)
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Catalog No. TMAC-04208
Alias ubiquitin specific peptidase 7 (herpes virus-associated), TEF1, HAUSP
Anti-USP7 Antibody (8N914) is a Rabbit antibody targeting USP7. Anti-USP7 Antibody (8N914) can be used in FCM,IHC,WB.
Anti-USP7 Antibody (8N914)
Anti-USP7 Antibody (8N914)
😃Good
Catalog No. TMAC-04208Alias ubiquitin specific peptidase 7 (herpes virus-associated), TEF1, HAUSP
Anti-USP7 Antibody (8N914) is a Rabbit antibody targeting USP7. Anti-USP7 Antibody (8N914) can be used in FCM,IHC,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $296 | 7-10 days | 7-10 days | |
| 100 μL | $497 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-USP7 Antibody (8N914) is a Rabbit antibody targeting USP7. Anti-USP7 Antibody (8N914) can be used in FCM,IHC,WB. |
| Synonyms | ubiquitin specific peptidase 7 (herpes virus-associated), TEF1, HAUSP |
| Ig Type | IgG |
| Clone | 8N914 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of USP7 on 293T cell using anti-USP7 antibody at 1/500 dilution. 2. Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-USP7 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-USP7 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti-USP7 antibody. Counter stained with hematoxylin. 5. Flow cytometric analysis of PC-3M cells with USP7 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.      |
| Application | |
| Recommended Dose | WB: 1:500-1000; IHC: 1:50; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | HAUSP (herpesvirus-associated ubiquitin-specific protease, USP7) is a ubiquitin-specific protease. HAUSP localizes predominantly to the nucleus, in a TD-dependent manner, where it associates with ND10. ND10 are small nuclear structures implicated in a variety of cellular processes including response to stress and interferons, oncogenesis, and viral infection. HAUSP binds strongly to Vmw110, a herpesvirus regulatory protein which has the ability to disrupt ND10. HAUSP, a novel p53-interacting protein, functions to deubiquitinize p53 in an important pathway for p53 stabilization. HAUSP strongly stabilizes p53 even in the presence of excess Mdm2, and also induces p53-dependent cell growth repression and apoptosis. The HAUSP protein is distributed in the nucleus in a micropunctate pattern with a limited number of larger discrete foci, some of which co-localize with PML in ND10. The gene encoding HAUSP maps to human chromosome band 16p13.2. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: human USP7 aa 100-200 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Theoretical: 128 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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