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δ-Sleep Inducing Peptide

🥰Excellent
Catalog No. T7107Cas No. 62568-57-4
Alias DSIP, Delta-Sleep Inducing Peptide

δ-Sleep Inducing Peptide (DSIP) is a neuropeptide exhibiting antioxidant and anxiolytic properties.

δ-Sleep Inducing Peptide

δ-Sleep Inducing Peptide

🥰Excellent
Catalog No. T7107Alias DSIP, Delta-Sleep Inducing PeptideCas No. 62568-57-4
δ-Sleep Inducing Peptide (DSIP) is a neuropeptide exhibiting antioxidant and anxiolytic properties.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$37In StockIn Stock
5 mg$56In StockIn Stock
10 mg$100In StockIn Stock
25 mg$205In StockIn Stock
50 mg$307In StockIn Stock
100 mg$461In Stock-
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Appearance:Solid
Color:White
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COA LCMS

Product Introduction

Bioactivity
Description
δ-Sleep Inducing Peptide (DSIP) is a neuropeptide exhibiting antioxidant and anxiolytic properties.
In vivo
Delta-Sleep Inducing Peptide(DSIP) and DSIP-12 significantly (*P<0.05 and **P<0.01) increased in delta and theta frequency bands and decreased the incidence, mean seizure grade and duration of metaphit convulsions. Suggest that DSIP and DSIP-12 may be considered as potential antiepileptics in the animal model[1].
Animal Research
The rats divided in four groups received (i.p.): saline; metaphit; metaphit+DSIP; and metaphit+DSIP-12, respectively. Metaphit-treated animals displaying seizure in eight previous tests received DSIP or DSIP-12 and afterwards audiogenic stimuli were applied at hourly intervals for the next 30 h. The animals were exposed to sound stimulation 60 min after metaphit administration and further on at hourly intervals. Incidence and severity of seizures were behaviorally analyzed. Selected EEGs and power spectra were recorded and analyzed[1].
SynonymsDSIP, Delta-Sleep Inducing Peptide
Chemical Properties
Molecular Weight848.81
FormulaC35H48N10O15
Cas No.62568-57-4
SmilesCC(NC(=O)C(N)Cc1c[nH]c2ccccc12)C(=O)NCC(=O)NCC(=O)NC(CC(O)=O)C(=O)NC(C)C(=O)NC(CO)C(=O)NCC(=O)NC(CCC(O)=O)C(O)=O
Relative Density.1.458 g/cm3
SequenceTrp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
Sequence ShortWAGGDASGE
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 10 mM, Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.1781 mL5.8906 mL11.7812 mL58.9060 mL
5 mM0.2356 mL1.1781 mL2.3562 mL11.7812 mL
10 mM0.1178 mL0.5891 mL1.1781 mL5.8906 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Δ-Sleep Inducing PeptideδSleep Inducing Peptideδ Sleep Inducing PeptideInhibitorinhibitAntioxidant
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