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Anti-CD31/PECAM-1 Antibody (1O74)
🥰Excellent
Catalog No. TMAY-03279
Anti-CD31/PECAM-1 Antibody (1O74) is a Rabbit antibody targeting CD31/PECAM-1. Anti-CD31/PECAM-1 Antibody (1O74) can be used in FCM.
Anti-CD31/PECAM-1 Antibody (1O74)
Anti-CD31/PECAM-1 Antibody (1O74)
🥰Excellent
Catalog No. TMAY-03279
Anti-CD31/PECAM-1 Antibody (1O74) is a Rabbit antibody targeting CD31/PECAM-1. Anti-CD31/PECAM-1 Antibody (1O74) can be used in FCM.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CD31/PECAM-1 Antibody (1O74) is a Rabbit antibody targeting CD31/PECAM-1. Anti-CD31/PECAM-1 Antibody (1O74) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 1O74 |
| Reactivity | Mouse |
| Verified Activity | Flow cytometric analysis of Mouse PECAM1(CD31) expression on BABL/c splenocytes. Cells were stained with purified anti-Mouse PECAM1(CD31) , then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| Application | FCM |
| Recommended Dose | FCM: 1:25-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD31/PECAM-1 (rM CD31/PECAM-1; TMPY-01619; NP_033868.3; Met1-Lys590). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | The Cluster of Differentiation 31 (CD31) adhesion molecule, also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1), is the only known member of the CAM family on platelets. CD31 protein is a 130-kDa transmembrane glycoprotein expressed by endothelial cells, platelets, monocytes, neutrophils, and certain T cell subsets. CD31 protein is also expressed in certain tumors, including epithelioid hemangioendothelioma, other vascular tumors, and histiocytic malignancies. CD31 plays a key role in removing aged neutrophils and tissue regeneration. CD31 protein mediates the homotypic or heterotypic cell adhesion by binding to itself or the leukocyte integrin αvβ3, and thus plays a role in neutrophil recruitment in inflammatory responses, transendothelial migration of leukocytes, as well as in cardiovascular development. |
| Conjucates | Unconjugated |
| Others Formats | APC/FITC/PE |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Mouse CD31/PECAM-1 Protein (TMPY-01619) |
| Antigen Species | Mouse |
| Biology Area | Hemangioblast Markers, ITIM/ITAM Immunoreceptors and Related Molecules |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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