Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CHO-CH2-PEG1-CH2-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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Description | CHO-CH2-PEG1-CH2-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Synonyms | CHO-CH2-PEG1-CH2-Boc |
Molecular Weight | 218.249 |
Formula | C10H18O5 |
CAS No. | 2230956-95-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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CHO-CH2-PEG1-CH2-Boc 2230956-95-1 CHO-CH-2-PEG1-CH2-Boc CHOCH2PEG1CH2Boc CHO CH2 PEG1 CH2 Boc inhibitor inhibit