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Phenols

Phenols are a class of chemical compounds consisting of a hydroxyl group (-OH) bonded directly to an aromatic hydrocarbon group, found in Ericaceae, Rosaceae, Vitaceae, Asteraceae, Labiatae, Boraginaceae,et al. Phenols have multiple bioactivities, such as antiseptic, bactericidal, fungicidal, antihelminitic, mild anaesthetic and calmative.

  • γ-Tocotrienol
    T1976814101-61-2
    γ-Tocotrienol (Plastochromanol) is one of the four types of tocotrienol, a type of vitamin E. Itl is also a radioprotector, antioxidant. It shows antitumor and antihypertensive effects in vivo.
    • $39
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  • Desaminotyrosine
    T2862501-97-3
    Desaminotyrosine (3-(4-Hydroxyphenyl)propionic acid) is a microbially associated metabolite. Desaminotyrosine protects from influenza through augmentation of type I interferon signaling.
    • $42
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  • Veratryl alcohol
    T065793-03-8
    3,4-Dimethoxybenzyl alcohol is a secondary metabolite of lignin-degrading fungi and is commonly used as a non-phenolic substrate to measure ligninolytic activity.Veratryl alcohol protects lignin peroxidase (LiP) from inactivation by H2O2 and prevents accumulation of LiP III compounds[3].
    • $42
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  • Pyrolin
    TN487195-71-6
    Pyrolin has a strong antifungal activity and exerts a potent impact on the ultrastructure of M.fructicola.
    • $29
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  • Gossypol
    T6518303-45-7
    Gossypol (BL 193) Acetate is a polyphenolic aldehyde that permeates cells and acts as an inhibitor for several dehydrogenase enzymes.
    • $35
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  • 2-methoxycinnamaldehyde
    T74521504-74-1
    2-methoxycinnamaldehyde is a natural compound of Cinnamomum cassia,has been widely studied with regard to its antitumor activity.
    • $41
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  • (-)-Epigallocatechin
    T2987970-74-1
    (-)-Epigallocatechin, the predominant flavonoid in green tea, possesses the unique ability to attach to unfolded native polypeptides, thereby inhibiting their transformation into amyloid fibrils.
    • $50
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  • 4-Hydroxybenzyl alcohol
    T3752623-05-2
    4-Hydroxybenzyl alcohol (P-Methylolphenol) exhibits beneficial effects in cerebral ischemic injury, has neuroprotective effect through upregulation of Nrf2, Prdx6, and PDI expression via the PI3K/Akt pathway. 4-Hydroxybenzyl alcohol inhibit the development of new blood vessels by targeting multiple mechanisms of the angiogenic process, may as a promising candidate for the establishment of anti-angiogenic treatment strategies in cancer therapy.
    • $29
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  • Forsythoside I
    T82771177581-50-8
    Forsythoside I, a caffeoyl phenylethanoid glycoside (CPG), may possess anti-inflammatory activities.
    • $110
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  • Guaiacol
    T130190-05-1
    Guaiacol (2-Methoxyphenol) is a precursor to various flavorants, such as eugenol and vanillin. Its derivatives are used medicinally as an expectorant, antiseptic, and local anesthetic. It also can be used as an indicator in chemical reactions that produce oxygen. When oxygen binds to it, the complex turns yellowish brown and absorbs light maximally at about 470 nm.
    • $42
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  • Triacetylresveratrol
    T566842206-94-0
    Triacetylresveratrol (Acetyl-trans-resveratrol) has anti-cancer activity,it inhibits the phosphorylation of STAT3 and NFκB, down-regulates Mcl-1, and up-regulates Bim and Puma in pancreatic cancer cells.
    • $68
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  • Protocatechualdehyde
    T3018139-85-5
    Protocatechualdehyde (3,4-Dihydroxybenzaldehyde), a natural polyphenol compound derived from radix Salviae Miltiorrhizae roots, exhibits diverse biological activities and finds extensive medicinal applications as an antioxidant, anti-aging, antibacterial, and anti-inflammatory agent.
    • $30
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  • Ethylparaben
    T0834120-47-8
    Ethylparaben (Ethyl parahydroxybenzoate) is a Standardized Chemical Allergen. The physiologic effect of ethylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity.
    • $50
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  • Methylnissolin-3-O-glucoside
    T571194367-42-7
    Methylnissolin-3-O-glucoside ((6aR, 11 aR)-3-hydroxy-9,l0-diMethoxy pt) has anti-inflammatory effects,antioxidant activity.
    • $98
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  • Methyl 3,4,5-trimethoxybenzoate
    T05721916-07-0
    Methyl EudesMate, synthesized from Gallic acid, has antioxidant activity and is commonly used in the production of sulfonamide synergist intermediates, trimethoprim (TMP) and many other drugs.
    • $46
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  • Oxyresveratrol
    T3S106829700-22-9
    1. Oxyresveratro can inhibit tyrosinase activity. 2. Oxyresveratro is useful to trauma models, as toxicity to glia could be beneficial by inhibiting reactive gliosis. 3. Oxyresveratrol (trans-Oxyresveratrol) has antioxidant activity, can reduce neuronal oxidative damage and protect hepatocytes against oxidative stress and mitochondrial dysfunction, which may be associated with activation of Nrf2.
    • $31
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  • Pterostilbene
    T2888537-42-8
    Pterostilbene is extracted from Pterocarpus indicus.
    • $40
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  • [6]-Gingerol
    T340523513-14-6
    [6]-Gingerol ((S)-(+)-[6]Gingerol), an antioxidant, protects HL-60 cells from oxidative stress. It has protective effects for Yous tumors in the pancreas, ovaries, breast tissue, the bowel, among other tissues.
    • $120
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  • Paradol
    T711327113-22-0
    Paradol ([6]-Gingerone) is a pungent phenolic substance found in ginger and other Zingiberaceae plants, and exhibits a variety of biological activities including anti-cancer, anti-inflammatory, and anti-oxidative activities,neuroprotective Effects.
    • $40
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  • α-Vitamin E
    T164859-02-9
    α-Vitamin E (Dexrabeprazole Sodium) is a naturally-occurring form of vitamin E, a fat-soluble vitamin with potent antioxidant properties.
    • $38
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  • Paeonol
    T2900552-41-0
    Paeonol (Peonol) is an active extraction from Paeonia suffruticosa. Paeonol inhibits MAO-A and MAO-B with IC50 of 54.6 μM and 42.5 μM, respectively.
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  • 2,6-Dimethoxybenzoic acid
    T37581466-76-8
    2,6-Dimethoxybenzoic acid is an o-methoxybenzoic acid and its derivatives that inhibit fungi and bacteria.
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  • Ethyl salicylate
    TN1625118-61-6
    Ethyl salicylate is a natural product
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  • 4-Methylcatechol
    T4779452-86-8
    4-Methylcatechol (3,4-Dihydroxytoluene) is a metabolite of homoprotocatechuic acid. It is both a substrate and a suicide inhibitor of Catechol 2,3-dioxygenase. 4-Methylcatechol (3,4-Dihydroxytoluene) is known to induce the production of brain-derived neurotrophic factor (BDNF). Recent studies have suggested that a lack of brain-derived neurotrophic factor (BDNF) in the limbic system may cause neuropathic pain.
    • $50
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  • Gallic acid
    T0877149-91-7
    Gallic acid (Benzoic acid) is found in almost all plants. Plants known for their high gallic acid content include gallnuts,grapes,tea,hops and oak bark.
    • $38
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  • Ginkgolic Acid
    T6S212322910-60-7
    Ginkgolic Acid (Romanicardic acid) C15:1 represses curli genes and prophage genes in EHEC.
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  • Methyl Paraben
    T372899-76-3
    The physiologic effect of Methyl Paraben (Nipagin) is by means of Increased Histamine Release, and Cell-mediated Immunity. Methyl Paraben (Nipagin) is an antimicrobial agent, preservative, flavouring agent. Methyl Paraben (Nipagin) is a constituent of cloudberry, yellow passion fruit, white wine, botrytised wine and Bourbon vanilla.The physiologic effect of Methyl Paraben (Nipagin) has been shown to exhibit anti-microbial function.
    • $42
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  • 1,2,4-Trihydroxybenzene
    T37705533-73-3
    1,2,4-Trihydroxybenzene (Benzene-1,2,4-triol) is a by-product of coffee bean roasting and is found in mouse, arabica coffee.1,2,4-Trihydroxybenzene is a benzotriol that increases Ca2+ concentration in rat thymic lymphocytes.
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  • Alnustone
    T4S017633457-62-4
    Alnustone ((4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one) exerts significant anti-inflammatory activity in the assay of carrageenin-induced hind paw edema in rats.
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  • Cannabigerol
    TN146525654-31-3
    Cannabigerol is a high affinity α±2-adrenergic receptor agonist, moderate affinity 5-HT1A receptor antagonist, and low affinity CB1 receptor antagonist ; also binds to the CB2 receptor; it can relieve interocular pressure, which may be of benefit in the treatment of glaucoma.
    • $148
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  • 3-Hydroxyphenylacetic acid
    T4829621-37-4
    3-Hydroxyphenylacetic acid is a rutin metabolite and an antioxidant. It has a protective biological activity in human. It is a substrate of enzyme 4-hydroxyphenylacetate 3-monooxygenase [EC 1.14.13.3] in the pathway tyrosine metabolism. 3-Hydroxyphenylace
    • $42
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  • Ethyl 4-hydroxyphenylacetate
    Fr1241517138-28-2
    Ethyl 4-hydroxyphenylacetate is a selective inhibitor of monoamine oxidase A.
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  • 4-Hydroxybenzyl cyanide
    Fr1674514191-95-8
    4-Hydroxybenzyl cyanide (4-Hydroxyphenylacetonitrile) shows strong antioxidative activity.
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  • Gnetifolin E
    TN5746140671-07-4
    Gnetifolin E is a new resveratrol trimer derivative from Gnetum brunonianum.
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  • 6-Bromovanillin
    TN722160632-40-8
    6-Bromovanillin is a biochemical reagent that can be used in the synthesis of caridopa, an aromatic amino acid decarboxylase inhibitor.
    • $29
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  • 2-Hydroxy-3-methoxy chalcone
    TN72267146-86-3
    2-Hydroxy-3-methoxy chalcone has anticancer activity and inhibits colon cancer.
    • $195
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  • 2,2'-Dihydroxy chalcone
    TN722415131-80-3
    2,2'-Dihydroxy chalcone is a potent inhibitor of β-glucuronidase (IC50=1.6±0.2 μM) and lysozyme (IC50=1.4±0.2 μM) release from rat neutrophils stimulated with fMLP/CB.2,2'-Dihydroxy chalcone has inhibitory activity against Escherichia coli, Shigella fowleri, Staphylococcus albicans and Staphylococcus aureus.
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  • Aucuparin
    TN34693687-28-3In house
    Aucuparin (2,6-dimethoxy-4-phenylphenol) is a plant antibiotic with anti-inflammatory activity. Aucuparin inhibited pulmonary fibrosis in mouse models induced by bleomycin (BLM). ABTS and FRAP showed clear scavenging activity. Aucuparin inhibited superoxide production of human neutrophils induced by fmlp, and its IC50 was 17.0μM.
    • $538
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  • Methylarbutin
    T198986032-32-2
    Methylarbutin (ß-PMP-Glc;4-Methoxyphenyl β-D-Glucopyranoside) is an ice recrystallization inhibitor (IRI)
    • $29
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  • Nor-rubrofusarin gentiobioside
    TN7249245724-08-7
    Nor-rubrofusarin gentiobioside is a natural product found in the leguminous plant Cassia vulgaris.
    • $195
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  • Caesappanin C
    T135891913319-59-1
    Caesappanin C, extracted from the heartwood of Indonesian Caesalpinia sappan L., shows strong proliferation stimulating activity against the primary osteoblastic cells in vitro.
    • $129
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  • Coretinphencone
    TN70901631711-77-7
    Coretinphencone is a natural product that is isolated from the buds of Coreopsis tinctoria Nutt.
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  • Diformylphloroglucinol
    TN72184396-13-8
    Diformylphloroglucinol (2,4,6-Trihydroxyisophthalaldehyde) is an acyl resorcinol isolated from the leaves of the Eucalyptus nigra tree and is a raw material for the synthesis of resorcinol compounds with antioxidant and antiulcer activity.
    • $54
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  • 2'-Hydroxy-3,4-dimethoxychalcone
    TN722519152-36-4
    2'-Hydroxy-3,4-dimethoxychalcone, a chalcone compound isolated from the roots of Sophora japonica, has antioxidant activity and inhibited the intracellular survival of Lactobacillus donovani Parasite EC.50 Values ranged between 0.39 and 0.41 μg/mL, which can be used in the study of diabetes, treatment of schistosomiasis, malaria and other infections.
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  • Usenamine A
    T836321428417-60-0In house
    Usenamine A is a small molecule compound derived from lichen Usnea longissima that has antitumor activity and can be used in the study of tumors.
    • $195
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  • 4-(Ethoxymethyl)phenol
    TN302957726-26-8
    4-(Ethoxymethyl)phenol (p-Hydroxybenzyl Et ether) is a small molecule compound extracted from Amburana cearensis with cytotoxic and antioxidant activity.
    • $80
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  • Henryoside
    TN420172021-23-9
    Henryoside is a natural product isolated from the herbs of Alangium chinense.
    • $179
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  • Butyl chlorogenate
    TN7230132741-56-1
    Butylchlorogenate is a natural compound isolated from Lonicera japonica, Urceola rosea.
    • $195
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  • Bryonamide B
    TN14575942-25-6
    Bryonamide B is a cucurbitane triterpene that can be extracted from Bryonia aspera.
    • $64
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  • Magnoloside B
    TN7134116872-05-0
    Magnoloside B, a phenylethanol glycoside from the fruit of Magnolia officinalis, is an α-glucosidase inhibitor with protective effects against free radical-induced oxidative damage and can be used in cancer research.
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