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Anti-SLC22A17 Polyclonal Antibody is a Rabbit antibody targeting SLC22A17. Anti-SLC22A17 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $221 | 7-10 days | |
100 μL | $373 | 7-10 days | |
200 μL | $527 | 7-10 days |
Description | Anti-SLC22A17 Polyclonal Antibody is a Rabbit antibody targeting SLC22A17. Anti-SLC22A17 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF. |
Alias | Solute carrier family 22 member 17, Slc22a17, Lipocalin-2 receptor, Brain-type organic cation transporter, Boct, 24p3 receptor (24p3R) |
Ig Type | IgG |
Reactivity | Human,Rat (predicted:Mouse,Dog,Pig,Cow) |
Verified Activity | 1. Tissue/cell: rat colon carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min; Incubation: Anti-Slc22A17 Y Polyclonal Antibody, Unconjugated (TMAB-01706) 1:300, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining. 2. Sample: Lane 1: SH-SY5Y (Human) Cell Lysate at 30 μg Lane 2: U2os (Human) Cell Lysate at 30 μg Lane 3: U87MG (Human) Cell Lysate at 30 μg Lane 4: A549 (Human) Cell Lysate at 30 μg Lane 5: Siha (Human) Cell Lysate at 30 μg Primary: Anti-Slc22A17 (TMAB-01706) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 58 kDa Observed band size: 61 kDa |
Application | WB,IHC-P,IHC-Fr,IF |
Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Subcellular Localization | Cell membrane; Multi-pass membrane protein. Vacuole membrane; Multi-pass membrane protein. Note=Upon LCN2-binding, it is internalized. |
Construction | Hybridoma Polyclonal Antibody |
Purification | Protein A purified |
Appearance | Liquid |
Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Research Background | SLC22A17 (solute carrier family 22 nember 17; organic cation transportor,).may act as a brain-specific organic ion transporter. The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of substrates including ions, sugar phosphates, drugs, neurotransmitters, nucleosides, amino acids, and peptides. They do so using the electrochemical potential of the transported substrates. Uniporters transport a single substrate, while symporters and antiporters transport two substrates in the same or in opposite directions, respectively, across membranes. MFS proteins are typically 400 to 600 amino acids in length, and the majority contain 12 transmembrane alpha helices (TMs) connected by hydrophilic loops. |
Immunogen | KLH conjugated synthetic peptide: human NGALR |
Antigen Species | Human |
Gene ID | |
Uniprot ID | |
Biology Area | Channels |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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