Powder: -20°C for 3 years | In solvent: -80°C for 1 year
15(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 15-lipoxygenase (15-LO) on arachidonic acid. It is either metabolized to 14,15-leukotriene A4 [1] or reduced to 15(S)-HETE by peroxidases.[2] [1] 15(S)-HpETE mediates a number of biological functions including the induction of c-fos and c-jun, and activation of AP-1. [3] 15(S)-HpETE inhibits prostacyclin synthesis in porcine aortic microsomes and bovine endothelial cells, and can cause the suicide inactivation of porcine 12-LO.[2][4][5]
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 μg | 35 days | $ 93.00 | |
50 μg | 35 days | $ 163.00 | |
100 μg | 35 days | $ 296.00 | |
250 μg | 35 days | $ 693.00 |
Description | 15(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 15-lipoxygenase (15-LO) on arachidonic acid. It is either metabolized to 14,15-leukotriene A4 [1] or reduced to 15(S)-HETE by peroxidases.[2] [1] 15(S)-HpETE mediates a number of biological functions including the induction of c-fos and c-jun, and activation of AP-1. [3] 15(S)-HpETE inhibits prostacyclin synthesis in porcine aortic microsomes and bovine endothelial cells, and can cause the suicide inactivation of porcine 12-LO.[2][4][5] |
Molecular Weight | 336.47 |
Formula | C20H32O4 |
CAS No. | 70981-96-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
0.1 M Na2CO3: 2 mg/mL
PBS (pH 7.2): 0.8 mg/mL
DMSO: Miscible
DMF: Miscible
Ethanol: Miscible
You can also refer to dose conversion for different animals. More
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15(S)-HpETE 70981-96-3 15HpETE 15(S)HpETE 15(S) HpETE inhibitor inhibit