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15(S)-HpETE
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Catalog No. T35943Cas No. 70981-96-3
Alias 15S-HpETE
15(S)-HpETE is a product of arachidonic acid formed in the 15-lipoxygenase pathway and inhibits angiogenesis. 15(S)-HpETE can upregulate the expression of CD31, E-selectin, and gene selectin in cells.
15(S)-HpETE
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Catalog No. T35943Alias 15S-HpETECas No. 70981-96-3
15(S)-HpETE is a product of arachidonic acid formed in the 15-lipoxygenase pathway and inhibits angiogenesis. 15(S)-HpETE can upregulate the expression of CD31, E-selectin, and gene selectin in cells.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μg | $133 | - | In Stock | |
| 50 μg | $236 | 35 days | 35 days | |
| 100 μg | $429 | 35 days | 35 days | |
| 250 μg | $983 | 35 days | 35 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Appearance:Liquid
Color:Transparent
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| Description | 15(S)-HpETE is a product of arachidonic acid formed in the 15-lipoxygenase pathway and inhibits angiogenesis. 15(S)-HpETE can upregulate the expression of CD31, E-selectin, and gene selectin in cells. |
| In vitro | 15(S)-HpETE is involved in the regulation of a variety of cell signaling pathways and biological processes by inducing the expression of c-fos and c-jun genes and activating AP-1 transcription factor. This regulatory mechanism is important for understanding inflammatory responses, cellular stress responses, and other diseases related to lipid metabolism. [1] |
| Synonyms | 15S-HpETE |
| Molecular Weight | 336.47 |
| Formula | C20H32O4 |
| Cas No. | 70981-96-3 |
| Smiles | [C@@H](/C=C/C=C\C/C=C\C/C=C\CCCC(O)=O)(CCCCC)OO |
| Storage | store at low temperature,keep away from direct sunlight,High Volatility | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 0.1 M Na2CO3: <1 mg/mL (Insoluble or slightly soluble.) PBS (pH 7.2): <1 mg/mL (Insoluble or slightly soluble.) DMSO: Miscible DMF: Miscible Ethanol: Miscible |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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