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FKBP25/FKBP3 Protein, Human, Recombinant (His)
(Synonyms: Rotamase, Rapamycin-selective 25 kDa immunophilin, PPIase FKBP3, Peptidyl-prolyl cis-trans isomerase FKBP3, Immunophilin FKBP25, FKBP-3, FKBP-25, FKBP25, FK506-binding protein 3, 25 kDa FKBP, 25 kDa FK506-binding protein) Copy Product InfoSynonyms: Rotamase, Rapamycin-selective 25 kDa immunophilin, PPIase FKBP3, Peptidyl-prolyl cis-trans isomerase FKBP3, Immunophilin FKBP25, FKBP-3, FKBP-25, FKBP25, FK506-binding protein 3, 25 kDa FKBP, 25 kDa FK506-binding protein
Catalog No. TMPJ-01068 Copy Product Info
FKBP25 contains 1 PPIase FKBP-type domain, belongs to the FKBP-type PPIase family. FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. FKBP3 is a cis-trans prolyl isomerase enzyme that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $39 | 7-10 days | 7-10 days | |
| 10 μg | $60 | 7-10 days | 7-10 days | |
| 20 μg | $83 | 7-10 days | 7-10 days | |
| 50 μg | $129 | 7-10 days | 7-10 days | |
| 100 μg | $219 | 7-10 days | 7-10 days | |
| 200 μg | $383 | 7-10 days | 7-10 days | |
| 500 μg | $806 | 7-10 days | 7-10 days | |
| 1 mg | $1,300 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | FKBP25 contains 1 PPIase FKBP-type domain, belongs to the FKBP-type PPIase family. FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. FKBP3 is a cis-trans prolyl isomerase enzyme that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin. |
| Species | Human |
| Expression System | E. coli |
| Tag | N-6xHis |
| Accession Number | Q00688 |
| Amino Acid | Met1-Asp224 |
| Construction | Met1-Asp224 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 1 mM DTT, 10% Glycerol, pH 8.0. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | Proteins are shipped with blue ice. |
| Synonyms | Rotamase, Rapamycin-selective 25 kDa immunophilin, PPIase FKBP3, Peptidyl-prolyl cis-trans isomerase FKBP3, Immunophilin FKBP25, FKBP-3, FKBP-25, FKBP25, FK506-binding protein 3, 25 kDa FKBP, 25 kDa FK506-binding protein |
| Research Background |
| Molecular Weight | 30 KDa (reducing condition) |
| Storage | Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: FKBP25/FKBP3 Protein, Human, Recombinant (His) chemical structure | FKBP25/FKBP3 Protein, Human, Recombinant (His) molecular weight
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