Serum Amyloid P Protein, Human, Recombinant (hFc)

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Catalog No. TMPY-06808

Serum Amyloid P Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.98 kDa and the accession number is P02743.

Serum Amyloid P Protein, Human, Recombinant (hFc)

Copy Product Info

Catalog No. TMPY-06808

Serum Amyloid P Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.98 kDa and the accession number is P02743.

Pack Size	Price	USA Warehouse	Global Warehouse
5 μg	$62	7-10 days	7-10 days
10 μg	$98	7-10 days	7-10 days
20 μg	$163	7-10 days	7-10 days
50 μg	$366	7-10 days	7-10 days

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In Stock Estimated shipping dateUSA Warehouse [1-2 days] Global Warehouse [5-7 days]

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User Guide of Recombinant Proteins

Product Information

Biological Activity	Immobilized Recombinant Human CD64 / FCGR1A Protein (ECD, His Tag) at 2 μg/ml (100 μl/well) can bind Recombinant Human Serum Amyloid P Protein (Fc Tag) , the EC50 is 4-12 ng/mL.
Description	Serum Amyloid P Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.98 kDa and the accession number is P02743.
Species	Human
Expression System	HEK293 Cells
Tag	C-hFc
Accession Number	P02743
Synonyms	SAP,PTX2,HEL-S-92n,amyloid P component, serum
Construction	A DNA sequence encoding the Human APCS (P02743) (Met1-Val223) was expressed with the Fc region of human IgG1 at the C-terminus. Predicted N terminal: His 20
Protein Purity	≥ 95 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.
Molecular Weight	49.98 kDa (predicted); 51.18 kDa (reducing conditions)
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, 10% Glycerol, 10% trehalose, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Research Background	Serum amyloid P component (SAP) is the identical serum form of amyloid P component (AP), a highly preserved plasma protein named for its ubiquitous presence in amyloid deposits. As a normal plasma protein first identified as the pentagonal constituent of in vivo pathological deposits called "amyloid". Serum amyloid P component represents another member of the pentraxin family, a highly conserved group of molecules that may play a role in innate immunity. SAP is a key negative regulator for innate immune responses to DNA and may be partly responsible for the insufficient immune responses after DNA vaccinations in humans. SAP suppression may be a novel strategy for improving efficacy of human DNA vaccines and requires further clinical investigations.