Shopping Cart
- Remove All
- Your shopping cart is currently empty
Ansamitocin P-3 (GMP) refers to the GMP grade reagents of Ansamitocin P-3. Ansamitocin p-3 (Maytansinol isobutyrate) is an inhibitor of microtubule with IC50 of 3.4 μM for tubulin polymerization.
Description | Ansamitocin P-3 (GMP) refers to the GMP grade reagents of Ansamitocin P-3. Ansamitocin p-3 (Maytansinol isobutyrate) is an inhibitor of microtubule with IC50 of 3.4 μM for tubulin polymerization. |
In vitro | Ansamitocin p-3 inhibits the proliferation in a concentration-dependent manner with IC50s of 20, 50, 140, and 150 pM for MCF-7, HeLa, EMT-6/AR1, and MDA-MB-231 cells in culture, respectively. Ansamitocin P3 binds to purified tubulin (Kd = 1.3 µM)[1]. |
Molecular Weight | 635.14 |
Formula | C32H43ClN2O9 |
Cas No. | 66584-72-3 |
Relative Density. | 1.29g/cm3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.