Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-Cadherin 16/CDH16 Antibody (9V223)

😃Good
Catalog No. TMAY-01326
Alias UNQ695/PRO1340, cadherin 16

Anti-Cadherin 16/CDH16 Antibody (9V223) is a Mouse antibody targeting Cadherin 16/CDH16. Anti-Cadherin 16/CDH16 Antibody (9V223) can be used in IHC-P.

Anti-Cadherin 16/CDH16 Antibody (9V223)

Anti-Cadherin 16/CDH16 Antibody (9V223)

😃Good
Catalog No. TMAY-01326Alias UNQ695/PRO1340, cadherin 16
Anti-Cadherin 16/CDH16 Antibody (9V223) is a Mouse antibody targeting Cadherin 16/CDH16. Anti-Cadherin 16/CDH16 Antibody (9V223) can be used in IHC-P.
Pack SizePriceAvailabilityQuantity
100 μL$199 7-10 days
Bulk & Custom
Add to Cart
Questions
View More
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
Anti-Cadherin 16/CDH16 Antibody (9V223) is a Mouse antibody targeting Cadherin 16/CDH16. Anti-Cadherin 16/CDH16 Antibody (9V223) can be used in IHC-P.
AliasUNQ695/PRO1340, cadherin 16
Ig Type
Monoclonal Mouse IgG1
Clone
9V223
Reactivity
Human
Verified Activity
Immunochemical staining of human CDH16 in human kidney with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections).
Application
IHC-P
Recommended Dose
IHC-P: 1:50-1:200
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human KSP-Cadherin / Cadherin-16 (rh KSP-Cadherin / Cadherin-16; TMPY-01763; NP_004053.1; Met1-Ala786). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundKSP-Cadherin/Cadherin-16 is a member of the cadherin superfamily, calcium-dependent, membrane-associated glycoproteins. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. KSP-Cadherin/Cadherin-16 can be detected at later stages of tubulogenesis during human renal development and in the distal tubules of adult kidneys, no expression was found by immunohistochemistry or Western blot analysis in RCC tumour tissues and several RCC cell lines. However, despite the lack of protein expression, mRNA synthesis of KSP-Cadherin/Cadherin-16 could be detected by reverse transcriptase-polymerase chain reaction analysis in all RCC tissues and most of the RCC cell lines studied, although at a reduced level. The loss of KSP-Cadherin/Cadherin-16 protein was only observed in the malignant part of the tumour kidneys, whereas in the normal part of the affected kidneys KSP-Cadherin/Cadherin-16 expression was clearly detected. These results indicate a downregulation of Ksp-cadherin in RCC and suggest a role for this cell adhesion molecule in tumour suppression.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human KSP-Cadherin / Cadherin-16 Protein (TMPY-01763)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

Sci Citations

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy Anti-Cadherin 16/CDH16 Antibody (9V223) | purchase Anti-Cadherin 16/CDH16 Antibody (9V223) | Anti-Cadherin 16/CDH16 Antibody (9V223) cost | order Anti-Cadherin 16/CDH16 Antibody (9V223)