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RKIP/PEBP1 Protein, Human, Recombinant

(Synonyms: RKIP, phosphatidylethanolamine binding protein 1, PEBP-1, PEBP, PBP, HEL-S-34, HEL-210, HCNPpp, HCNP) Copy Product Info

Synonyms: RKIP, phosphatidylethanolamine binding protein 1, PEBP-1, PEBP, PBP, HEL-S-34, HEL-210, HCNPpp, HCNP

Catalog No. TMPY-00146 Copy Product Info
Phosphatidylethanolamine-binding protein 1 (PEBP1), also known as Raf kinase inhibitor protein, belongs to PEBP family of proteins. It is known to interact with many proteins that are mainly involved in pathways that monitor cell proliferation and differentiation. PEBP1 in many cells interacts with several pathways, namely MAPK, GRK2, NF-small ka, CyrillicB, etc. that keeps the cell proliferation and differentiation in check. This protein is expressed by many cells in humans, including neurons where it is predominantly involved in production of choline acetyltransferase. Deregulated PEBP1 is known to cause cancer, diabetic nephropathy and neurodegenerative diseases like Alzheimer's and dementia.
RKIP/PEBP1 Protein, Human, Recombinant
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$79-In Stock
10 μg$129-In Stock
20 μg$208-In Stock
50 μg$4197-10 days7-10 days
100 μg$8127-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:> 95 % as determined by SDS-PAGE.
Appearance:Lyophilized powder
Color:White
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Product Introduction

Bioactivity
Bioactivity
Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
Phosphatidylethanolamine-binding protein 1 (PEBP1), also known as Raf kinase inhibitor protein, belongs to PEBP family of proteins. It is known to interact with many proteins that are mainly involved in pathways that monitor cell proliferation and differentiation. PEBP1 in many cells interacts with several pathways, namely MAPK, GRK2, NF-small ka, CyrillicB, etc. that keeps the cell proliferation and differentiation in check. This protein is expressed by many cells in humans, including neurons where it is predominantly involved in production of choline acetyltransferase. Deregulated PEBP1 is known to cause cancer, diabetic nephropathy and neurodegenerative diseases like Alzheimer's and dementia.
Species
Human
Expression System
E. coli
TagTag Free
Accession NumberD9IAI1
ConstructionA DNA sequence encoding the human PEBP1 (NP_002558.1) (Met1-Lys187) was expressed. Predicted N terminal: Met
Protein Purity
> 95 % as determined by SDS-PAGE.
EndotoxinPlease contact us for more information.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM TRIS, 10% glycerol, pH 8.0.Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
ReconstitutionA Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
SynonymsRKIP, phosphatidylethanolamine binding protein 1, PEBP-1, PEBP, PBP, HEL-S-34, HEL-210, HCNPpp, HCNP
Research Background
Chemical Properties
Molecular Weight21.1 kDa (predicted)
Storage & Solubility Information
StorageStore at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: RKIP/PEBP1 Protein, Human, Recombinant chemical structure | RKIP/PEBP1 Protein, Human, Recombinant molecular weight