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6-Prenylapigenin
(Synonyms: 6-Prenyl-4',5,7-trihydroxyflavone, 6-C-Prenylapigenin, 4',5,7-Trihydroxy-6-prenylflavone) Copy Product Info
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Synonyms: 6-Prenyl-4',5,7-trihydroxyflavone, 6-C-Prenylapigenin, 4',5,7-Trihydroxy-6-prenylflavone
Catalog No. TN3009 Copy Product Info
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6-Prenylapigenin is a prenylated flavonoid that exists in the stems and leaves of Maclura pomifera. 6-Prenylapigenin exhibits cytotoxicity against cancer cells such as leukemia cells and solid tumor cells. 6-Prenylapigenin is additionally relevant in cancer-related cellular research models for investigating prenylated flavonoid interactions with tumor-associated signaling pathways and for biochemical profiling of flavonoid-induced cellular response mechanisms.
Cas No. 68097-13-2
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 mg | $540 | Inquiry | Inquiry |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | 6-Prenylapigenin is a prenylated flavonoid that exists in the stems and leaves of Maclura pomifera. 6-Prenylapigenin exhibits cytotoxicity against cancer cells such as leukemia cells and solid tumor cells. 6-Prenylapigenin is additionally relevant in cancer-related cellular research models for investigating prenylated flavonoid interactions with tumor-associated signaling pathways and for biochemical profiling of flavonoid-induced cellular response mechanisms. |
| Targets & IC50 | MCF-7 cells:1.7 μM, PF-382 cells:11.2 μM, CaSki cells:13.8 μM |
| In vitro | Methods:The antiproliferative activity of 6-Prenylapigenin (4',5,7-Trihydroxy-6-prenylflavone) against various tumor cell lines was determined, and the corresponding IC₅₀ values were calculated. Results:This compound exhibited cytotoxicity against multiple cancer cells. Its IC₅₀ values for MCF-7, PF-382 and Caski cells were 1.7 μM, 11.2 μM and 13.8 μM, respectively [2]. |
| Synonyms | 6-Prenyl-4',5,7-trihydroxyflavone, 6-C-Prenylapigenin, 4',5,7-Trihydroxy-6-prenylflavone |
| Molecular Weight | 338.35 |
| Formula | C20H18O5 |
| Cas No. | 68097-13-2 |
| Smiles | O=C1C=C(OC2=CC(O)=C(C(O)=C12)CC=C(C)C)C=3C=CC(O)=CC3 |
| Relative Density. | no data available |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 µL Tween 80 and mix well until fully clarified.
3) Add 450 µL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
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Related Tags: 6-Prenylapigenin chemical structure | 6-Prenylapigenin in vitro | 6-Prenylapigenin formula | 6-Prenylapigenin molecular weight
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