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Gypenoside LXXV

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Catalog No. T38495Cas No. 110261-98-8

Gypenoside LXXV is a natural saponin discovered in Panax ginseng that binds to the glucocorticoid receptor and translocates into the cell nucleus, thereby promoting wound healing and upregulating CTGF.

Gypenoside LXXV

Gypenoside LXXV

😃Good
Purity: 98.66%
Catalog No. T38495Cas No. 110261-98-8
Gypenoside LXXV is a natural saponin discovered in Panax ginseng that binds to the glucocorticoid receptor and translocates into the cell nucleus, thereby promoting wound healing and upregulating CTGF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$113-In Stock
5 mg$289-In Stock
10 mg$428-In Stock
25 mg$728-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:98.66%
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Product Introduction

Bioactivity
Description
Gypenoside LXXV is a natural saponin discovered in Panax ginseng that binds to the glucocorticoid receptor and translocates into the cell nucleus, thereby promoting wound healing and upregulating CTGF.
In vitro
Gypenoside LXXV (1.0-100 μM, 48 hours) can dose-dependently inhibit the proliferation of three cancer cell lines (Homo sapiens cervical cancer cell line HeLa, mouse melanoma cell line B16, Homo sapiens breast cancer cell line MDA-MB-231). When the administration concentration reaches 50 μM, it can almost completely inhibit the proliferation of all tested cancer cells [1].
Chemical Properties
Molecular Weight785.03
FormulaC42H72O13
Cas No.110261-98-8
SmilesC[C@]12[C@@]([C@]3(C)[C@@](CC1)(C(C)(C)[C@@H](O)CC3)[H])(C[C@@H](O)[C@]4([C@@]2(C)CC[C@@]4([C@@](O[C@@H]5O[C@H](CO[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)[C@@H](O)[C@H](O)[C@H]5O)(CCC=C(C)C)C)[H])[H])[H]
ColorWhite
AppearanceSolid
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80.00 mg/mL (101.91 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.2738 mL6.3692 mL12.7384 mL63.6918 mL
5 mM0.2548 mL1.2738 mL2.5477 mL12.7384 mL
10 mM0.1274 mL0.6369 mL1.2738 mL6.3692 mL
20 mM0.0637 mL0.3185 mL0.6369 mL3.1846 mL
50 mM0.0255 mL0.1274 mL0.2548 mL1.2738 mL
100 mM0.0127 mL0.0637 mL0.1274 mL0.6369 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

Gypenoside LXXV
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