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Gypenoside LXXV

Name: Gypenoside LXXV
Brand: TargetMol
SKU: T38495
Price: 113 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T38495Cas No. 110261-98-8

Gypenoside LXXV is a natural saponin discovered in Panax ginseng that binds to the glucocorticoid receptor and translocates into the cell nucleus, thereby promoting wound healing and upregulating CTGF.

Gypenoside LXXV

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Purity: 98.66%

Catalog No. T38495Cas No. 110261-98-8

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$113	-	In Stock
5 mg	$289	-	In Stock
10 mg	$428	-	In Stock
25 mg	$728	-	In Stock
50 mg	$987	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:98.66%

Appearance:Solid

Color:White

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Gypenoside LXXV is a natural saponin discovered in Panax ginseng that binds to the glucocorticoid receptor and translocates into the cell nucleus, thereby promoting wound healing and upregulating CTGF.
In vitro	Gypenoside LXXV (1.0-100 μM, 48 hours) can dose-dependently inhibit the proliferation of three cancer cell lines (Homo sapiens cervical cancer cell line HeLa, mouse melanoma cell line B16, Homo sapiens breast cancer cell line MDA-MB-231). When the administration concentration reaches 50 μM, it can almost completely inhibit the proliferation of all tested cancer cells [1].

Chemical Properties

Molecular Weight	785.03
Formula	C₄₂H₇₂O₁₃
Cas No.	110261-98-8
Smiles	[H][C@@]1(CC[C@]2(C)[C@]1([H])[C@H](O)C[C@]1([H])[C@@]3(C)CC[C@H](O)C(C)(C)[C@]3([H])CC[C@@]21C)[C@](C)(CCC=C(C)C)O[C@@H]1O[C@H](CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O

Storage & Solubility Information

Storage

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80.00 mg/mL (101.91 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.2738 mL	6.3692 mL	12.7384 mL	63.6918 mL
5 mM	0.2548 mL	1.2738 mL	2.5477 mL	12.7384 mL
10 mM	0.1274 mL	0.6369 mL	1.2738 mL	6.3692 mL
20 mM	0.0637 mL	0.3185 mL	0.6369 mL	3.1846 mL
50 mM	0.0255 mL	0.1274 mL	0.2548 mL	1.2738 mL
100 mM	0.0127 mL	0.0637 mL	0.1274 mL	0.6369 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc