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Eritadenine

Name: Eritadenine
Brand: TargetMol
SKU: T25385
Rating: 4.5 (1 reviews)

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Catalog No. T25385Cas No. 23918-98-1

Alias Lentysine, Lentinacin, D-Eritadenine

Eritadenine (Lentinacin) is a mushroom-derived compound that acts on the adenosine P-site in adipocyte plasma membranes, lowering cholesterol levels and altering phospholipid composition in rat models of hyperhomocysteinemia, used in anxiety disorder studies.

Eritadenine

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Catalog No. T25385Alias Lentysine, Lentinacin, D-EritadenineCas No. 23918-98-1

Pack Size	Price	Availability
1 mg	$115	35 days
5 mg	$460	35 days
10 mg	$748	35 days

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Product Introduction

Bioactivity

Description	Eritadenine (Lentinacin) is a mushroom-derived compound that acts on the adenosine P-site in adipocyte plasma membranes, lowering cholesterol levels and altering phospholipid composition in rat models of hyperhomocysteinemia, used in anxiety disorder studies.
Targets&IC50	ACE:0.091 μM
In vitro	Eritadenine inhibited angiotensin-converting enzyme (ACE) activity with IC50 of 0.091 μM. [1]
In vivo	Eritadenine (50 mg/kg, fed) induces its cholesterol-lowering effects by modulating the fatty acid and molecular profile of phosphatidylcholine (PC) regardless of the presence or absence of exogenous cholesterol. [2]
Synonyms	Lentysine, Lentinacin, D-Eritadenine

Chemical Properties

Molecular Weight	253.22
Formula	C₉H₁₁N₅O₄
Cas No.	23918-98-1
Smiles	C([C@H]([C@H](C(O)=O)O)O)N1C=2C(N=C1)=C(N)N=CN2
Relative Density.	1.92g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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Keywords

Eritadenine