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PSG1 Protein, Human, Recombinant (His)

Catalog No. TMPY-00552
Synonyms: PS-β-G-1, PSBG-1, PS-beta-G-1, CD66f, pregnancy specific β-1-glycoprotein 1, B1G1, DHFRP2, FL-NCA-1/2, PSGGA, pregnancy specific beta-1-glycoprotein 1, PS-beta-C/D, PS-β-C/D, PSBG1, PBG1, SP1, PSG95, PSGIIA

PSG1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 44.9 kDa and the accession number is P11464-1.

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PSG1 Protein, Human, Recombinant (His)
Pack Size Availability Price/USD Quantity
100 μg 5 days $ 700.00
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Biological Description
Technical Params
Product Properties
Description PSG1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 44.9 kDa and the accession number is P11464-1.
Species Human
Expression System HEK293 Cells
Tag C-His
Accession Number P11464-1
Synonyms PS-β-G-1, PSBG-1, PS-beta-G-1, CD66f, pregnancy specific β-1-glycoprotein 1, B1G1, DHFRP2, FL-NCA-1/2, PSGGA, pregnancy specific beta-1-glycoprotein 1, PS-beta-C/D, PS-β-C/D, PSBG1, PBG1, SP1, PSG95, PSGIIA
Construction The Human PSG1 (NP_001171754.1) (Met1-Pro419) was expressed with a polyhistidine tag at the C-terminus.
Protein Purity > 95 % as determined by SDS-PAGE.
Molecular Weight 44.9 kDa (predicted)
Endotoxin < 1.0 EU/μg of the protein as determined by the LAL method.
Formulation Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Shipping

In general, Lyophilized powders are shipping with blue ice.

Research Background Pregnancy-specific glycoproteins (PSGs) are a family of Ig-like proteins secreted by specialized placental cells. The PSG1 structure is composed of a single Ig variable region-like N-terminal domain and three Ig constant region-like domains termed A1, A2, and B2. Members of the human and murine PSG family have been shown to induce anti-inflammatory cytokines from monocytes and macrophages and to stimulate angiogenesis. Two distinct domains of PSG1 are involved in the regulation of TGF-beta1 and provide a mechanistic framework for how PSGs modulate the immunoregulatory environment at the maternal-fetal interface for successful pregnancy outcome.

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Keywords

PSG1 Protein, Human, Recombinant (His) PS-b-G-1 SP-1 PS-β-G-1 DHFRP-2 PSBG-1 PS-beta-G-1 PBG 1 PSBG 1 CD66f pregnancy specific β-1-glycoprotein 1 B1G1 PBG-1 DHFRP2 FL-NCA-1/2 PSGGA SP 1 pregnancy specific beta-1-glycoprotein 1 PS-b-C/D PSG 95 pregnancy specific b-1-glycoprotein 1 PS-beta-C/D DHFRP 2 PS-β-C/D PSBG1 PBG1 SP1 PSG95 PSG-95 PSGIIA recombinant recombinant-proteins proteins protein

 

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