Moracin P

Name: Moracin P
Brand: TargetMol
SKU: TN1952
Price: 114 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN1952Cas No. 102841-46-3

Moracin P, a 2-arylbenzofuran derivative isolated from Mori Cortex Radicis, shows potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1). This compound reduces oxygen-glucose deprivation-induced reactive oxygen species generation while demonstrating neuroprotective and anti-inflammatory properties.

Moracin P

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Catalog No. TN1952Cas No. 102841-46-3

Pack Size	Price	Availability	Quantity
1 mg	$114	In Stock

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Product Introduction

Bioactivity

Description	Moracin P, a 2-arylbenzofuran derivative isolated from Mori Cortex Radicis, shows potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1). This compound reduces oxygen-glucose deprivation-induced reactive oxygen species generation while demonstrating neuroprotective and anti-inflammatory properties.
Targets&IC50	SH-SY5Y cells:10.4μM (EC50)
In vitro	Moracin P enhances the cell viability of SH-SY5Y cells in a dose-dependent manner with an EC50 value of 10.4 μM. [1]

Chemical Properties

Molecular Weight	326.34
Formula	C₁₉H₁₈O₅
Cas No.	102841-46-3
Smiles	O[C@@H]1CC=2C=C3C(=CC2OC1(C)C)OC(=C3)C4=CC(O)=CC(O)=C4
Relative Density.	1.349 g/cm3 (Predicted)

Storage & Solubility Information

Storage	keep away from moisture,keep away from direct sunlight \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Solubility Information	DMSO: ≥ 80 mg/mL, Sonication is recommended.

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

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