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Anti-P Glycoprotein Antibody (1U603) (Synonyms: PGY1, P gp, P glycoprotein 1, Multidrug resistance protein 1|...)
Catalog No. TMAB-01311 Copy Product Info
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Anti-P Glycoprotein Antibody (1U603) is a Rabbit antibody targeting P Glycoprotein. Anti-P Glycoprotein Antibody (1U603) can be used in IF, IHC-Fr, IHC-P, WB.
Anti-P Glycoprotein Antibody (1U603)
Copy Product Info🥰Excellent
Catalog No. TMAB-01311
Synonyms PGY1, P gp, P glycoprotein 1, Multidrug resistance protein 1, Multidrug resistance 1, MDR1, GP170, Doxorubicin resistance, Colchicin sensitivity, CLCS, CD243, ATP-binding cassette sub-family B member 1, ATP binding cassette, sub family B(MDR/TAP), member 1, ABCB1, ABC20
Anti-P Glycoprotein Antibody (1U603) is a Rabbit antibody targeting P Glycoprotein. Anti-P Glycoprotein Antibody (1U603) can be used in IF, IHC-Fr, IHC-P, WB.
Anti-P Glycoprotein Antibody
(1U603)
(1U603)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 μL | $154 | 7-10 days | 7-10 days | |
| 50 μL | $272 | 7-10 days | 7-10 days | |
| 100 μL | $488 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-P Glycoprotein Antibody (1U603) is a Rabbit antibody targeting P Glycoprotein. Anti-P Glycoprotein Antibody (1U603) can be used in IF, IHC-Fr, IHC-P, WB. |
| Synonyms | PGY1, P gp, P glycoprotein 1, Multidrug resistance protein 1, Multidrug resistance 1, MDR1, GP170, Doxorubicin resistance, Colchicin sensitivity, CLCS, CD243, ATP-binding cassette sub-family B member 1, ATP binding cassette, sub family B(MDR/TAP), member 1, ABCB1, ABC20 |
| Ig Type | IgG |
| Clone | 1U603 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Paraformaldehyde-fixed, paraffin embedded Mouse Liver; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with P Glycoprotein Monoclonal Antibody, Unconjugated (TMAB-01311) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit) and DAB staining. 2. Paraformaldehyde-fixed, paraffin embedded Human Cerebrum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with P Glycoprotein Monoclonal Antibody, Unconjugated (TMAB-01311) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit) and DAB staining. 3. Paraformaldehyde-fixed, paraffin embedded Human Kidney; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with P Glycoprotein Monoclonal Antibody, Unconjugated (TMAB-01311) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit) and DAB staining. 4. Paraformaldehyde-fixed, paraffin embedded Mouse Cerebrum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with P Glycoprotein Monoclonal Antibody, Unconjugated (TMAB-01311) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining. 5. Paraformaldehyde-fixed, paraffin embedded Rat Cerebrum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with P Glycoprotein Monoclonal Antibody, Unconjugated (TMAB-01311) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining. 6. Paraformaldehyde-fixed, paraffin embedded Mouse Kidney; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with P Glycoprotein Monoclonal Antibody, Unconjugated (TMAB-01311) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining. 7. Paraformaldehyde-fixed, paraffin embedded Rat Liver; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with P Glycoprotein Monoclonal Antibody, Unconjugated (TMAB-01311) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining. 8. Paraformaldehyde-fixed, paraffin embedded Human Liver; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with P Glycoprotein Monoclonal Antibody, Unconjugated (TMAB-01311) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining.         |
| Application | |
| Recommended Dose | IF=1:100-500; IHC-Fr=1:100-500; IHC-P=1:100-500; WB=1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Multi-pass membrane protein. |
| Tissue Specificity | Expressed in liver, kidney, small intestine and brain. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.02% Proclin300. |
| Concentration | 1 mg/mL |
| Research Background | P Glycoprotein, the product of the MDR1 gene, is expressed in distinct non-malignant cells, typically cells with secretory and excretory functions. It is assumed to function as an ATP-dependent drug efflux pump with broad substrate specificity. The highest expression of P Glycoprotein has been observed in kidney (proximal tubules), liver (bile canaliculi), adrenal gland and intestine, suggesting that the primary role of P Glycoprotein is in the normal secretion of physiological metabolites and ingested chemicals into bile, urine and the lumen of the intestinal tract. Elevated levels of P Glycoprotein have also been reported in multidrug-resistant cell lines and in colon, endometrial, ovarian, and breast tumors, as well as in sarcomas and leukemias / lymphomas. |
| Immunogen | Recombinant Protein: Human P-glycoprotein 1 protein |
| Antigen Species | Human |
| Gene Name | ABCB1 |
| Gene ID | |
| Protein Name | ATP-dependent translocase ABCB1 |
| Uniprot ID | |
| Biology Area | P glycoproteins,ATPases,Channels,Side Population,Surface Molecules |
| Function | Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells. Subunit : Interacts with PSMB5. |
| Molecular Weight | Theoretical: 141 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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