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Anti-P Glycoprotein Antibody (1U603) is a Rabbit antibody targeting P Glycoprotein. Anti-P Glycoprotein Antibody (1U603) can be used in IF,IHC-Fr,IHC-P.
| Pack Size | Price | Availability | Quantity | 
|---|---|---|---|
| 25 μL | $154 | 7-10 days | |
| 50 μL | $272 | 7-10 days | |
| 100 μL | $488 | 7-10 days | 
| Description | Anti-P Glycoprotein Antibody (1U603) is a Rabbit antibody targeting P Glycoprotein. Anti-P Glycoprotein Antibody (1U603) can be used in IF,IHC-Fr,IHC-P. | 
| Synonyms | PGY1, P gp, P glycoprotein 1, Multidrug resistance protein 1, Multidrug resistance 1, MDR1, GP170, Doxorubicin resistance, Colchicin sensitivity, CLCS, CD243, ATP-binding cassette sub-family B member 1, ATP binding cassette, sub family B(MDR/TAP), member 1, ABCB1, ABC20 | 
| Ig Type | IgG | 
| Clone | 1U603 | 
| Reactivity | Human,Mouse,Rat | 
| Verified Activity | 1. Paraformaldehyde-fixed, paraffin embedded Mouse Liver; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with P Glycoprotein Monoclonal Antibody, Unconjugated (TMAB-01311) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit) and DAB staining. 2. Paraformaldehyde-fixed, paraffin embedded Human Cerebrum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with P Glycoprotein Monoclonal Antibody, Unconjugated (TMAB-01311) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit) and DAB staining. 3. Paraformaldehyde-fixed, paraffin embedded Human Kidney; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with P Glycoprotein Monoclonal Antibody, Unconjugated (TMAB-01311) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit) and DAB staining. 4. Paraformaldehyde-fixed, paraffin embedded Mouse Cerebrum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with P Glycoprotein Monoclonal Antibody, Unconjugated (TMAB-01311) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining. 5. Paraformaldehyde-fixed, paraffin embedded Rat Cerebrum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with P Glycoprotein Monoclonal Antibody, Unconjugated (TMAB-01311) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining. 6. Paraformaldehyde-fixed, paraffin embedded Mouse Kidney; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with P Glycoprotein Monoclonal Antibody, Unconjugated (TMAB-01311) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining. 7. Paraformaldehyde-fixed, paraffin embedded Rat Liver; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with P Glycoprotein Monoclonal Antibody, Unconjugated (TMAB-01311) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining. 8. Paraformaldehyde-fixed, paraffin embedded Human Liver; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with P Glycoprotein Monoclonal Antibody, Unconjugated (TMAB-01311) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining.         | 
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IF: 1:100-500; IHC-Fr: 1:100-500 | 
| Antibody Type | Monoclonal | 
| Host Species | Rabbit | 
| Subcellular Localization | Cell membrane; Multi-pass membrane protein. | 
| Tissue Specificity | Expressed in liver, kidney, small intestine and brain. | 
| Construction | Recombinant Antibody | 
| Purification | Protein A purified | 
| Appearance | Liquid | 
| Formulation | 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.02% Proclin300. | 
| Concentration | 1 mg/mL | 
| Immunogen | Recombinant Protein: Human P-glycoprotein 1 protein | 
| Antigen Species | Human | 
| Gene Name | ABCB1 | 
| Gene ID | |
| Protein Name | ATP-dependent translocase ABCB1 | 
| Uniprot ID | |
| Biology Area | P glycoproteins,ATPases,Channels,Side Population,Surface Molecules | 
| Function | Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells. Subunit : Interacts with PSMB5. | 
| Molecular Weight | Theoretical: 141 kDa. | 
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. | 
| Transport | Shipping with blue ice. | 

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