Fc epsilon RI alpha/FCER1a Protein, Human, Recombinant (His)

Name: Fc epsilon RI alpha/FCER1a Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPK-00149
Rating: 4.5 (1 reviews)

(Synonyms: Fc-ε RI-α, FcERI, FCER1A, Fc-epsilon RI-α, Fc-epsilon RI-alpha, FCE1A, Fc ε RI α/FCER1a, Fc epsilon RI α/FCER1a) Copy Product Info

Synonyms: Fc-ε RI-α, FcERI, FCER1A, Fc-epsilon RI-α, Fc-epsilon RI-alpha, FCE1A, Fc ε RI α/FCER1a, Fc epsilon RI α/FCER1a

Catalog No. TMPK-00149 Copy Product Info

Known susceptibility genes to atopy and asthma have been identified by linkage or associations with clinical phenotypes, including total serum IgE levels. IgE-mediated sensitivity reactions require a high-affinity IgE receptor (FcepsilonRI), which immobilizes the immunoglobulin on the surface of the effector cells, mostly mast cells and basophils. Similarly to the previously investigated beta subunit of the receptor, FCER1A is a good candidate for a quantitative trait locus (QTL) in allergic diseases, and appears to participate in the systemic regulation of IgE levels.

Fc epsilon RI alpha/FCER1a Protein, Human, Recombinant (His)

Pack Size	Price	USA Stock	Global Stock
5 µg	$41	7-10 days	7-10 days
10 µg	$62	7-10 days	7-10 days
20 µg	$98	7-10 days	7-10 days
50 µg	$188	7-10 days	7-10 days
100 µg	$313	7-10 days	7-10 days
200 µg	$568	7-10 days	7-10 days
500 µg	$1,260	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Immobilized Human Fc epsilon RI alpha, His Tag at 0.2μg/ml (100μl/well) on the plate. Dose response curve for Anti-Fc epsilon RI alpha Antibody, hFc Tag with the EC50 of 4.0ng/ml determined by ELISA.
Description	Known susceptibility genes to atopy and asthma have been identified by linkage or associations with clinical phenotypes, including total serum IgE levels. IgE-mediated sensitivity reactions require a high-affinity IgE receptor (FcepsilonRI), which immobilizes the immunoglobulin on the surface of the effector cells, mostly mast cells and basophils. Similarly to the previously investigated beta subunit of the receptor, FCER1A is a good candidate for a quantitative trait locus (QTL) in allergic diseases, and appears to participate in the systemic regulation of IgE levels.
Species	Human
Expression System	HEK293 Cells
Tag	C-His
Accession Number	P12319-1
Construction	Val26-Gln205
Protein Purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	Fc-ε RI-α, FcERI, FCER1A, Fc-epsilon RI-α, Fc-epsilon RI-alpha, FCE1A, Fc ε RI α/FCER1a, Fc epsilon RI α/FCER1a
Research Background	Known susceptibility genes to atopy and asthma have been identified by linkage or associations with clinical phenotypes, including total serum IgE levels. IgE-mediated sensitivity reactions require a high-affinity IgE receptor (FcepsilonRI), which immobilizes the immunoglobulin on the surface of the effector cells, mostly mast cells and basophils. Similarly to the previously investigated beta subunit of the receptor, FCER1A is a good candidate for a quantitative trait locus (QTL) in allergic diseases, and appears to participate in the systemic regulation of IgE levels.

Chemical Properties

Molecular Weight

22.1 kDa (predicted). Due to glycosylation, the protein migrates to 48-65 kDa based on Tris-Bis PAGE result.

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Related Tags: Fc epsilon RI alpha/FCER1a Protein, Human, Recombinant (His) chemical structure | Fc epsilon RI alpha/FCER1a Protein, Human, Recombinant (His) molecular weight