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3-(3,6-dichloro-9H-carbazol-9-yl)propanoic acid

🥰Excellent
Catalog No. T50021Cas No. 300816-42-6

3-(3,6-dichloro-9H-carbazol-9-yl)propanoic acid (DCPPA) is an ASIC3 inhibitor that effectively blocks ASIC3-mediated pain and inflammation. It has been shown to have potential applications in the treatment of other diseases such as stroke, epilepsy and cancer.

3-(3,6-dichloro-9H-carbazol-9-yl)propanoic acid

3-(3,6-dichloro-9H-carbazol-9-yl)propanoic acid

🥰Excellent
Purity: 97.85%
Catalog No. T50021Cas No. 300816-42-6
3-(3,6-dichloro-9H-carbazol-9-yl)propanoic acid (DCPPA) is an ASIC3 inhibitor that effectively blocks ASIC3-mediated pain and inflammation. It has been shown to have potential applications in the treatment of other diseases such as stroke, epilepsy and cancer.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$50In StockIn Stock
10 mg$75In StockIn Stock
25 mg$128In StockIn Stock
50 mg$192In StockIn Stock
100 mg$287In StockIn Stock
200 mg$431In StockIn Stock
500 mg$713-In Stock
1 mL x 10 mM (in DMSO)$66In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:97.85%
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COA LCMS HNMR

Product Introduction

Bioactivity
Description
3-(3,6-dichloro-9H-carbazol-9-yl)propanoic acid (DCPPA) is an ASIC3 inhibitor that effectively blocks ASIC3-mediated pain and inflammation. It has been shown to have potential applications in the treatment of other diseases such as stroke, epilepsy and cancer.
Chemical Properties
Molecular Weight308.159
FormulaC15H11Cl2NO2
Cas No.300816-42-6
SmilesOC(=O)CCN1C2=CC=C(Cl)C=C2C2=C1C=CC(Cl)=C2
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 55 mg/mL (178.48 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.2451 mL16.2254 mL32.4508 mL162.2539 mL
5 mM0.6490 mL3.2451 mL6.4902 mL32.4508 mL
10 mM0.3245 mL1.6225 mL3.2451 mL16.2254 mL
20 mM0.1623 mL0.8113 mL1.6225 mL8.1127 mL
50 mM0.0649 mL0.3245 mL0.6490 mL3.2451 mL
100 mM0.0325 mL0.1623 mL0.3245 mL1.6225 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Tech Support

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Keywords

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