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Anti-ACE Polyclonal Antibody is a Rabbit antibody targeting ACE. Anti-ACE Polyclonal Antibody can be used in WB,ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $220 | 7-10 days | |
100 μL | $374 | 7-10 days | |
200 μL | $529 | 7-10 days |
Description | Anti-ACE Polyclonal Antibody is a Rabbit antibody targeting ACE. Anti-ACE Polyclonal Antibody can be used in WB,ELISA. |
Alias | Kininase II, EC 3.4.15.1, Dipeptidyl carboxypeptidase I, DCP DCP1, CD antigen CD143, Angiotensin-converting enzyme |
Ig Type | IgG |
Reactivity | Mouse,Rat (predicted:Human,Dog,Pig,Cow) |
Verified Activity | Sample: Lane 1: Mouse Lung tissue lysates Lane 2: Mouse Testis tissue lysates Lane 3: Rat Lung tissue lysates Lane 4: Rat Testis tissue lysates Primary: Anti-ACE (TMAB-00031) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 147 kDa Observed band size: 110,180 kDa |
Application | WB,ELISA |
Recommended Dose | WB: 1:500-2000; ELISA: 1:5000-10000 |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Subcellular Localization | Angiotensin-converting enzyme, soluble form: Secreted. Cell membrane; Single-pass type I membrane protein. |
Construction | Hybridoma Polyclonal Antibody |
Purification | Protein A purified |
Appearance | Liquid |
Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Research Background | Angiotensin Converting enzyme is involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. ACE converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilatator. ACE exists in two forms, a 170KD somatic form and a 90KD germinal form. The somatic form is expressed by endothelial cells (especially those of lung capillaries and arterioles), epithelial cells (especially in proximal renal tubules and small intestine), by some neuronal cells and variably by some macrophages and T lymphocytes. The germinal form is expressed by spermatozoa. |
Immunogen | KLH conjugated synthetic peptide: human ACE1 |
Antigen Species | Human |
Gene ID | |
Uniprot ID | |
Biology Area | Response to hypoxia,Serum Proteins,Vasoconstriction,ACEs,Cardiovascular ELISA kits,Vitamins / minerals,Hypoxia,Vitamins / Minerals,Surface Molecules |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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