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Anti-TLR4 Antibody-HRP (8D178)
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Catalog No. TMAY-00341H
Alias toll-like receptor 4, TOLL, TLR-4, TLR4, CD284, ARMD10
Anti-TLR4 Antibody-HRP (8D178) is a HRP-conjugated Rabbit antibody targeting TLR4. Anti-TLR4 Antibody-HRP (8D178) can be used in ELISA.
Anti-TLR4 Antibody-HRP (8D178)
Anti-TLR4 Antibody-HRP (8D178)
😃Good
Catalog No. TMAY-00341HAlias toll-like receptor 4, TOLL, TLR-4, TLR4, CD284, ARMD10
Anti-TLR4 Antibody-HRP (8D178) is a HRP-conjugated Rabbit antibody targeting TLR4. Anti-TLR4 Antibody-HRP (8D178) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μg | $292 | 7-10 days |
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Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: ELISA Reactivity: Human |
| Alias | toll-like receptor 4, TOLL, TLR-4, TLR4, CD284, ARMD10 |
| Ig Type | Rabbit IgG |
| Clone | 8D178 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 0.1-1 μg/mL |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human TLR4 (rh TLR4; TMPY-02904; O00206-1; Met1-Lys631), conjugated with horseradish-peroxidase (HRP). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | TLR4, also known as TLR-4, is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. TLR4 is most abundantly expressed in placenta, and in myelomonocytic subpopulation of the leukocytes. TLR 4 has also been designated as CD284 (cluster of differentiation 284). It has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. TLR4 Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). It acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. It is also involved in LPS-independent inflammatory responses triggered by Ni(2+). |
| Conjucates | HRP |
| Others Formats | Unconjugated |
| Antibody Types Available | 2 |
| Immunogen | Recombinant Protein: Human TLR4 Protein (TMPY-02904) |
| Antigen Species | Human |
| Biology Area | Neuroinflammation |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. Keep away from direct sunlight. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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