Anti-CYBB Polyclonal Antibody

Name: Anti-CYBB Polyclonal Antibody
Brand: TargetMol
SKU: TMAB-00514
Rating: 4.5 (1 reviews)

(Synonyms: Superoxide-generating NADPH oxidase heavy chain subunit, p22 phagocyte B-cytochrome, NOX2, Neutrophil cytochrome b 91 kDa polypeptide, NADPH oxidase 2, Heme-binding membrane glycoprotein gp91phox, gp91-phox, gp91-1, Cytochrome b-245 heavy chain, Cytochrome b(558) subunit beta (Cytochrome b558 subunit beta), CYBB, CGD91-phox) Copy Product Info

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Synonyms: Superoxide-generating NADPH oxidase heavy chain subunit, p22 phagocyte B-cytochrome, NOX2, Neutrophil cytochrome b 91 kDa polypeptide, NADPH oxidase 2, Heme-binding membrane glycoprotein gp91phox, gp91-phox, gp91-1, Cytochrome b-245 heavy chain, Cytochrome b(558) subunit beta (Cytochrome b558 subunit beta), CYBB, CGD91-phox

Catalog No. TMAB-00514 Copy Product Info

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Anti-CYBB Polyclonal Antibody is a Rabbit antibody targeting CYBB. Anti-CYBB Polyclonal Antibody can be used in WB.

Anti-CYBB Polyclonal Antibody

Pack Size	Price	USA Stock	Global Stock
50 μL	$220	7-10 days	7-10 days
100 μL	$374	7-10 days	7-10 days
200 μL	$527	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Instruction Manual of Detection Antibody

Product Introduction

Bioactivity

Description	Anti-CYBB Polyclonal Antibody is a Rabbit antibody targeting CYBB. Anti-CYBB Polyclonal Antibody can be used in WB.
Synonyms	Superoxide-generating NADPH oxidase heavy chain subunit, p22 phagocyte B-cytochrome, NOX2, Neutrophil cytochrome b 91 kDa polypeptide, NADPH oxidase 2, Heme-binding membrane glycoprotein gp91phox, gp91-phox, gp91-1, Cytochrome b-245 heavy chain, Cytochrome b(558) subunit beta (Cytochrome b558 subunit beta), CYBB, CGD91-phox
Ig Type	IgG
Reactivity	Human,Mouse,Rat (predicted:Chicken,Dog,Pig,Cow,Horse,Rabbit)

Application	WB
Recommended Dose	WB=1:500-2000
Antibody Type	Polyclonal
Host Species	Rabbit
Subcellular Localization	Membrane.
Construction	Polyclonal Antibody
Purification	Protein A purified
Appearance	Liquid
Formulation	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration	1 mg/mL
Research Background	NOX2/gp91phox is a critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. It also functions as a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc. Defects in CYBB are a cause of X-linked chronic granulomatous disease (X-CGD). X-CGD is characterized by the failure of activated phagocytes to generate superoxide. Patients suffer from life-threatening bacterial/fungal infections.

Antigen Details

Immunogen	KLH conjugated synthetic peptide: human NOX2
Antigen Species	Human
Gene Name	CYBB
Gene ID	1536
Protein Name	Cytochrome b-245 heavy chain
Uniprot ID	P04839
Biology Area	Cellular metabolic process,Cytotoxic Cells
Function	Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc.