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Synonyms: triggering receptor expressed on myeloid cells 1
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
| Description | Anti-TREM-1 Polyclonal Antibody 2 is a Rabbit antibody targeting TREM-1. Anti-TREM-1 Polyclonal Antibody 2 can be used in FCM,WB. |
| Synonyms | triggering receptor expressed on myeloid cells 1 |
| Ig Type | IgG |
| Reactivity | Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-2000; FCM: 1ug/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Isoform 1: Cell membrane; Single-pass type I membrane protein (Potential). Isoform 2: Secreted (Potential). |
| Tissue Specificity | Highly expressed in adult liver, lung and spleen than in corresponding fetal tissue. Also expressed in the lymph node, placenta, spinal cord and heart tissues. Expression is more elevated in peripheral blood leukocytes than in the bone marrow and in norma |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011]. |
| Immunogen | KLH conjugated synthetic peptide: mouse TREM1 |
| Antigen Species | Mouse |
| Gene Name | TREM1 |
| Gene ID | |
| Protein Name | Triggering receptor expressed on myeloid cells 1 |
| Uniprot ID | |
| Biology Area | Macrophage / Inflamm. |
| Function | Stimulates neutrophil and monocyte-mediated inflammatory responses. Triggers release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Amplifier of inflammatory responses that are triggered by bacterial and fungal infections and is a crucial mediator of septic shock (By similarity). |
| Molecular Weight | Theoretical: 23 kDa. Actual: 25 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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