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Anti-TREM-1 Polyclonal Antibody 2 is a Rabbit antibody targeting TREM-1. Anti-TREM-1 Polyclonal Antibody 2 can be used in FCM,WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $222 | 7-10 days | |
100 μL | $372 | 7-10 days | |
200 μL | $527 | 7-10 days |
Description | Anti-TREM-1 Polyclonal Antibody 2 is a Rabbit antibody targeting TREM-1. Anti-TREM-1 Polyclonal Antibody 2 can be used in FCM,WB. |
Synonyms | triggering receptor expressed on myeloid cells 1 |
Ig Type | IgG |
Reactivity | Mouse,Rat |
Verified Activity | 1. Sample: kidney (Mouse) Lysate at 40 μg Primary: Anti-TREM1 (TMAB-01892) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 23 kDa Observed band size: 25 kDa 2. Sample: Liver (Rat) Lysate at 40 μg Primary: Anti-TREM1 (TMAB-01892) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 23 kDa Observed band size: 25 kDa 3. Blank control (black line): Mouse spleen (Black). Primary Antibody (green line): Rabbit Anti-TREM1 antibody (TMAB-01892) Dilution: 1 μg/10^6 cells; Isotype Control Antibody (orange line): Rabbit IgG. Secondary Antibody (white blue line): Goat anti-rabbit IgG-PE Dilution: 1 μg/test. Protocol The cells were fixed with 4% paraformaldehyde for 10 min at room temperature. The cells were then incubated in 5% BSA to block non-specific protein-protein interactions for 30 min at room temperature. Cells stained with Primary Antibody for 30 min at room temperature The secondary antibody used for 40 min at room temperature. Acquisition of 10,000 events was performed. |
Application | |
Recommended Dose | WB: 1:500-2000; FCM: 1ug/Test |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Subcellular Localization | Isoform 1: Cell membrane; Single-pass type I membrane protein (Potential). Isoform 2: Secreted (Potential). |
Tissue Specificity | Highly expressed in adult liver, lung and spleen than in corresponding fetal tissue. Also expressed in the lymph node, placenta, spinal cord and heart tissues. Expression is more elevated in peripheral blood leukocytes than in the bone marrow and in norma |
Construction | Polyclonal Antibody |
Purification | Protein A purified |
Appearance | Liquid |
Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Concentration | 1 mg/mL |
Research Background | This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011]. |
Immunogen | KLH conjugated synthetic peptide: mouse TREM1 |
Antigen Species | Mouse |
Gene Name | TREM1 |
Gene ID | |
Protein Name | Triggering receptor expressed on myeloid cells 1 |
Uniprot ID | |
Biology Area | Macrophage / Inflamm. |
Function | Stimulates neutrophil and monocyte-mediated inflammatory responses. Triggers release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Amplifier of inflammatory responses that are triggered by bacterial and fungal infections and is a crucial mediator of septic shock (By similarity). |
Molecular Weight | Theoretical: 23 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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