Anti-IL-15 Polyclonal Antibody

Name: Anti-IL-15 Polyclonal Antibody
Brand: TargetMol
SKU: TMAB-00944
Rating: 4.5 (1 reviews)

(Synonyms: interleukin 15, IL-15) Copy Product Info

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Synonyms: interleukin 15, IL-15

Catalog No. TMAB-00944 Copy Product Info

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Anti-IL-15 Polyclonal Antibody is a Rabbit antibody targeting IL-15. Anti-IL-15 Polyclonal Antibody can be used in FCM, ICC/IF, IF, IHC-Fr, IHC-P.

Anti-IL-15 Polyclonal Antibody

Pack Size	Price	USA Stock	Global Stock
50 μL	$221	7-10 days	7-10 days
100 μL	$374	7-10 days	7-10 days
200 μL	$528	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:1mg/ml

Appearance:Liquid

Color:Transparent

Resource Download

COA Instruction Manual of Detection Antibody

Product Introduction

Bioactivity

Description	Anti-IL-15 Polyclonal Antibody is a Rabbit antibody targeting IL-15. Anti-IL-15 Polyclonal Antibody can be used in FCM, ICC/IF, IF, IHC-Fr, IHC-P.
Synonyms	interleukin 15, IL-15
Ig Type	IgG
Reactivity	Human,Mouse (predicted:Rat)

Application	FCM ICC/IF IF IHC-Fr IHC-P
Recommended Dose	FCM=3 μg/Test; ICC/IF=1:100-500; IF=1:100-500; IHC-Fr=1:100-500; IHC-P=1:100-500
Antibody Type	Polyclonal
Host Species	Rabbit
Subcellular Localization	Isoform IL15-S48AA: Secreted. Isoform IL15-S21AA: Cytoplasm. Nucleus. Note=IL15-S21AA is not secreted, but rather is stored intracellularly, appearing in the nucleus and cytoplasmic components.
Tissue Specificity	Most abundant in placenta and skeletal muscle. It is also detected in the heart, lung, liver and kidney. IL15-S21AA is preferentially expressed in tissues such as testis and thymus.
Construction	Polyclonal Antibody
Purification	Protein A purified
Appearance	Liquid
Formulation	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration	1 mg/mL
Research Background	IL15 (114 amino acids) is a cytokine that regulates T and natural killer cell activation and proliferation. It has a predicted molecular mass of approximately 12.5 kDa. Human IL15 shares approximately 97% and 73% amino acid sequence identity with simian and mouse IL15, respectively. Both human and simian IL15 are active on mouse cells. IL15 was initially isolated from the simian kidney epithelial cell line CV1/EBNA. It has also been isolated from mouse and human cell sources. The cytokines IL15 and IL2 share many biological properties and stimulatory activities (T, B, and NK cells). Both IL15 and IL2 stimulate mouse CTLL2 cells. In activated peripheral blood T lymphocytes, IL2 is highly expressed but the expression of IL15 is not detectable. There is no sequence homology between IL15 and IL2, though computer modeling indicates both possess a four alpha helical bundle structure. IL15 competes for binding sites with IL2, as both IL2 and IL15 stimulate the growth of cells through the IL2 receptor. IL15 mRNA is expressed in many cell types and tissues including adherent peripheral blood mononuclear cells, fibroblasts, and epithelial cells, monocytes, placenta, and skeletal muscle.

Antigen Details

Immunogen	KLH conjugated synthetic peptide: human IL-15
Antigen Species	Human
Gene Name	IL15
Gene ID	3600
Protein Name	Interleukin-15
Uniprot ID	P40933
Biology Area	Interleukins,Antiviral Signaling,Interleukins,NK Cells,Obesity
Function	Cytokine that stimulates the proliferation of T-lymphocytes. Stimulation by IL-15 requires interaction of IL-15 with components of IL-2R, including IL-2R beta and probably IL-2R gamma but not IL-2R alpha.