8-NH2-ATP

Name: 8-NH2-ATP
Brand: TargetMol
SKU: T40455
Rating: 4.5 (1 reviews)

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Catalog No. T40455Cas No. 35874-49-8

Alias 8-NH2-ATP, 8-Aminoadenosine-5'-O-triphosphate

8-NH2-ATP is an inactive derivative of adenosine triphosphate (ATP), synthesized from 8-NH2-Ado. It has been documented that 8-NH2-Ado exhibits potent properties, as evidenced by its ability to induce apoptosis-associated cleavage of poly(ADP-ribose) polymerase.

8-NH2-ATP

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Catalog No. T40455Alias 8-NH2-ATP, 8-Aminoadenosine-5'-O-triphosphateCas No. 35874-49-8

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
25 mg	$1,520	Inquiry	Inquiry

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Product Introduction

Bioactivity

Description	8-NH2-ATP is an inactive derivative of adenosine triphosphate (ATP), synthesized from 8-NH2-Ado. It has been documented that 8-NH2-Ado exhibits potent properties, as evidenced by its ability to induce apoptosis-associated cleavage of poly(ADP-ribose) polymerase.
In vitro	The substantial intracellular accumulation of 8-NH2-ATP impedes RNA and DNA synthesis in both glucocorticoid-sensitive and glucocorticoid-resistant myeloma cell lines[1][2].
Synonyms	8-NH2-ATP, 8-Aminoadenosine-5'-O-triphosphate

Chemical Properties

Molecular Weight	522.20
Formula	C₁₀H₁₇N₆O₁₃P₃
Cas No.	35874-49-8
Relative Density.	2.76 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

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