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Anti-Prostasin/PRSS8 Antibody (9T600)
😃Good
Catalog No. TMAY-00556
Alias protease, serine, 8
Anti-Prostasin/PRSS8 Antibody (9T600) is a Rabbit antibody targeting Prostasin/PRSS8. Anti-Prostasin/PRSS8 Antibody (9T600) can be used in ELISA.
Anti-Prostasin/PRSS8 Antibody (9T600)
Anti-Prostasin/PRSS8 Antibody (9T600)
😃Good
Catalog No. TMAY-00556Alias protease, serine, 8
Anti-Prostasin/PRSS8 Antibody (9T600) is a Rabbit antibody targeting Prostasin/PRSS8. Anti-Prostasin/PRSS8 Antibody (9T600) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Antigen Details
Chemical Properties
| Description | Anti-Prostasin/PRSS8 Antibody (9T600) is a Rabbit antibody targeting Prostasin/PRSS8. Anti-Prostasin/PRSS8 Antibody (9T600) can be used in ELISA. |
| Alias | protease, serine, 8 |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 9T600 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human Prostasin / PRSS8 (rh PRSS8; TMPY-00905; NP_002764.1; Ala 30-Arg 322). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Prostasin (Prss8), also known as channel activating protease 1 (CAP1), is a trypsinlike serine peptidase, and plays important roles in epithelial physiology. It is originally purified as an active, soluble enzyme from human seminal fluid and is highly expressed in prostate, lung, kidney, salivary gland and pancreas. Prostasin is expressed as a glycosyl-phosphatidylinositol (GPI)-anchored membrane protein in prostate epithelial cells, and also exists as a secreted proteolytic enzyme possibly via tryptic cleavage of its COOH-terminal hydrophobic domain. Prostasin is found to activate the epithelial sodium channel (ENaC) which is tightly regulated and is critical for maintaining salt and fluid balance in the lung and kidney in both normal and pathological conditions. Accordingly, prostasin has been proposed as a target for therapeutic inhibition in cystic fibrosis. Besides, prostasin inhibits prostate and breast cancer cell invasion in vitro, suggesting a functional role as a suppressor of tumor invasion, as well as a regulator of gene expression during inflammation. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human PRSS8 protein (TMPY-00905) |
| Antigen Species | Human |
| Biology Area | Serine Proteases and Regulators |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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