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Anti-Phospho-PERK (Thr982) Polyclonal Antibody 2
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Catalog No. TMAC-03153
Anti-Phospho-PERK (Thr982) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PERK (Thr982). Anti-Phospho-PERK (Thr982) Polyclonal Antibody can be used in IHC.
Anti-Phospho-PERK (Thr982) Polyclonal Antibody 2
Anti-Phospho-PERK (Thr982) Polyclonal Antibody 2
😃Good
Catalog No. TMAC-03153
Anti-Phospho-PERK (Thr982) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PERK (Thr982). Anti-Phospho-PERK (Thr982) Polyclonal Antibody can be used in IHC.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $218 | 7-10 days | |
| 100 μL | $318 | 7-10 days |
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Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Phospho-PERK (Thr982) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PERK (Thr982). Anti-Phospho-PERK (Thr982) Polyclonal Antibody can be used in IHC. |
| Ig Type | IgG |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1:50-100 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis. Serves as a critical effector of unfolded protein response (UPR)-induced G1 growth arrest due to the loss of cyclin-D1 (CCND1) |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of threonine 982(R-H-T(p)-G-Q) derived from Human PEK/PERK |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Actual: 125 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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